Evidence map›Paper›PMID 33124883›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2021

NO-induced vasodilation correlates directly with BP in smooth muscle-Na/Ca exchanger-1-engineered mice: elevated BP does not attenuate endothelial function.

Youhua Wang, Jin Zhang, W Gil Wier, Ling Chen, Mordecai P Blaustein

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Sensational site: the sodium pump ouabain-binding site and its ligands.American journal of physiology. Cell physiology · 2024
    Review
  3. Article
  4. Article
  5. Review
  6. Biomedicines · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Youhua WangDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland.
Jin ZhangDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland.
W Gil WierDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland.
Ling ChenDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland.
Mordecai P BlausteinDepartment of Physiology, University of Maryland School of Medicine, Baltimore, Maryland.
University of Maryland, Baltimore · US

Funding

CALCIUM AND SODIUM TRANSPORT IN VASCULAR SMOOTH MUSCLER01HL045215 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI BLAUSTEIN, MORDECAI P, HAMLYN, JOHN · 1990 to 2012
$4.1M
Na+/Ca2+ Exchanger type-1 in Arterial Contraction and Salt-induced HypertensionR01HL107654 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI WIER, WITHROW GIL · 2011 to 2015
$1.8M
Alpha-2 Na+ Pumps, [Ca2+], Arterial Contraction & HypertensionR01HL107555 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI BLAUSTEIN, MORDECAI P · 2012 to 2015
$1.5M
NHLBI NIH HHS R01 HL045215NHLBI NIH HHS R01 HL107555NHLBI NIH HHS R01 HL107654
6 · The paper itself

Abstract

Arterial smooth muscle Na

Indexed as

Arterial PressureVasodilationAnimalsArteriesCalcium SignalingCyclic GMPEndothelium, VascularMaleMiceMice, Inbred C57BLMice, KnockoutMuscle, Smooth, VascularNitric OxideSodium-Calcium ExchangerCyclic GMPNCX1 protein, mouseNitric OxideSodium-Calcium Exchangeracetylcholinemesenteric arterymyogenic tonesodium nitroprussidevasodilation

Identifiers

PMID33124883
PMCPMC7847073
OpenAlexW3097620605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.