Evidence map›Paper›PMID 33124814›Full record

ArticleAnalytical chemistry2020

Microchip-Based Structure Determination of Disease-Relevant p53.

Maria J Solares, G M Jonaid, William Y Luqiu, Yanping Liang, Madison C Evans, William J Dearnaley, Zhi Sheng, Deborah F Kelly

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. High-Resolution Imaging of Human Cancer Proteins Using Microprocessor Materials.Chembiochem : a European journal of chemical biology · 2022
    Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Maria J SolaresMolecular, Cellular, and Integrative Biosciences Graduate Program, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, United States.
G M JonaidBioinformatics and Genomics Graduate Program, Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802, United States.
William Y LuqiuCenter for Structural Oncology, Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Yanping LiangFralin Biomedical Research Institute at VTC, Roanoke, Virginia 24016, United States.
Madison C EvansDepartment of Biomedical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802, United States.
William J DearnaleyDepartment of Biomedical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Zhi ShengFralin Biomedical Research Institute at VTC, Roanoke, Virginia 24016, United States.
Deborah F KellyDepartment of Biomedical Engineering, Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0002-7341-7435
Pennsylvania State University · USBiomedical Research Institute · US

Funding

Multi-scale imaging of breast cancer proteins during DNA repairR01CA219700 · NCI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI KELLY, DEBORAH F · 2018 to 2022
$2.1M
Hot Spot Analysis of the Breast Cancer Susceptibility ProteinR01CA227261 · NCI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI KELLY, DEBORAH F · 2018 to 2022
$2.0M
Tunable Microchip Sorting of BRCA1 Nuclear AssembliesR01CA193578 · NCI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI KELLY, DEBORAH F · 2015 to 2020
$1.8M
Cryo-EM analysis of PI3K signaling complexes in glioblastomaR21CA245631 · NCI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI KELLY, DEBORAH F, SHENG, ZHI · 2020 to 2021
$428k
NCI NIH HHS R01 CA193578NCI NIH HHS R01 CA219700NCI NIH HHS R01 CA227261NCI NIH HHS R21 CA245631
6 · The paper itself

Abstract

The tumor suppressor protein TP53 (p53) plays a multifaceted role in all cells of the human body. Mutations in the

Indexed as

DiseaseMicrochip Analytical ProceduresCell Line, TumorHumansProtein MultimerizationProtein Structure, QuaternaryTumor Suppressor Protein p53Tumor Suppressor Protein p53

Identifiers

PMID33124814
PMCPMC7816086
OpenAlexW3094898584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.