ArticleJournal of neural engineering2020
Acoustoelectric imaging of deep dipoles in a human head phantom for guiding treatment of epilepsy.
Article in Journal of neural engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Biological current source imaging method based on acoustoelectric effect: A systematic review.Frontiers in neuroscience · 2022Pooled it
- Hadamard-encoded synthetic beamforming for high frame rate acoustoelectric current source imaging.Ultrasonics · 2026Article
- Neuronavigation-Guided Transcranial Acoustoelectric Brain Imaging: A New Modality for High Resolution Electrical Brain Mapping.IEEE transactions on bio-medical engineering · 2025Article
- Noninvasive Intracranial Source Signal Localization and Decoding with High Spatiotemporal Resolution.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- Acoustoelectric Time-Reversal for Ultrasound Phase-Aberration Correction.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2023Article
- Acoustoelectric brain imaging with different conductivities and acoustic distributions.Frontiers in physiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveThis study employs a human head model with real skull to demonstrate the feasibility of transcranial acoustoelectric brain imaging (tABI) as a new modality for electrical mapping of deep dipole sources during treatment of epilepsy with much better resolution and accuracy than conventional mapping methods. APPROACH: This technique exploits an interaction between a focused ultrasound (US) beam and tissue resistivity to localize current source densities as deep as 63 mm at high spatial resolution (1 to 4 mm) and resolve fast time-varying currents with sub-ms precision. MAIN
resultsDetection thresholds through a thick segment of the human skull at biologically safe US intensities was below 0.5 mA and within range of strong currents generated by the human brain. SIGNIFICANCE: This work suggests that 4D tABI may emerge as a revolutionary modality for real-time high-resolution mapping of neuronal currents for the purpose of monitoring, staging, and guiding treatment of epilepsy and other brain disorders characterized by abnormal rhythms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.