Evidence map›Paper›PMID 33124533›Full record

ReviewThe American journal of tropical medicine and hygiene2020

Antibody Correlates of Protection from Clinical

Karen E S Hamre, Bartholomew N Ondigo, James S Hodges, Sheetij Dutta, Michael Theisen, George Ayodo, Chandy C John

Open access · bronzeAbstract readReview
In one paragraph

Review in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Host-parasite interactions duringFrontiers in immunology · 2022
    Review
  11. Article
  12. Opportunities for Subnational Malaria Elimination in High-Burden Countries.The American journal of tropical medicine and hygiene · 2020
    Article
  13. Antibody Profiles toThe American journal of tropical medicine and hygiene · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Karen E S Hamre1Division of Global Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Bartholomew N Ondigo4Department of Biochemistry and Molecular Biology, Egerton University, Nakuru, Kenya.
James S Hodges7Division of Biostatistics, University of Minnesota, Minneapolis, Minnesota.
Sheetij Dutta8Walter Reed Army Institute for Research, Silver Spring, Maryland.
Michael Theisen9Statens Serum Institut, Copenhagen, Denmark.
George Ayodo5Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Chandy C John1Division of Global Pediatrics, University of Minnesota, Minneapolis, Minnesota.
Kenya Medical Research Institute · KEUniversity of Minnesota · USCDC Foundation · USStatens Serum Institut · DKWalter Reed Army Institute of Research · US

Funding

Northern/Pacific Universities Global Health Research Training ConsortiumR25TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI KOLARS, JOSEPH C., NERURKAR, VIVEK RAMCHANDRA · 2012 to 2016
$5.9M
Translational Research in Malaria Transmission and Immunity in KenyaD43TW008085 · FIC · UNIVERSITY OF MINNESOTA · PI JOHN, CHANDY C. · 2008 to 2012
$752k
FIC NIH HHS D43 TW008085FIC NIH HHS R25 TW009345
6 · The paper itself

Abstract

Immune correlates of protection against clinical malaria are difficult to ascertain in low-transmission areas because of the limited number of malaria cases. We collected blood samples from 5,753 individuals in a Kenyan highland area, ascertained malaria incidence in this population over the next 6 years, and then compared antibody responses to 11

Indexed as

AdolescentAdultAgedAntibodies, ProtozoanAntibody FormationAntigens, ProtozoanCase-Control StudiesChildChild, PreschoolFemaleHumansIncidenceKenyaMalaria, FalciparumMaleMiddle AgedAntibodies, ProtozoanAntigens, ProtozoanProtozoan Proteins

Identifiers

PMID33124533
PMCPMC7695051
OpenAlexW3094757408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.