Evidence map›Paper›PMID 33124070›Full record

ArticleEquine veterinary journal2021

Equine influenza vaccination in the UK: Current practices may leave horses with suboptimal immunity.

Amie Wilson, Gina Pinchbeck, Rachel Dean, Catherine McGowan

Abstract read
In one paragraph

Article in Equine veterinary journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amie WilsonDepartment of Equine Clinical Science, Institute of Veterinary and Ecological Sciences, University of Liverpool, Neston, Cheshire, UK.ORCID https://orcid.org/0000-0002-5987-180X
Gina PinchbeckDepartment of Equine Clinical Science, Institute of Veterinary and Ecological Sciences, University of Liverpool, Neston, Cheshire, UK.
Rachel DeanVet Partners, Leeman House, York, UK.
Catherine McGowanDepartment of Equine Clinical Science, Institute of Veterinary and Ecological Sciences, University of Liverpool, Neston, Cheshire, UK.ORCID https://orcid.org/0000-0002-1946-9584

Funding

MSD Veterinary Research Bursary
6 · The paper itself

Abstract

backgroundVaccination is integral to preventive healthcare. Despite numerous guidelines on equine vaccination, evidence of current vaccination practices is lacking.

objectivesTo describe current vaccination practices advised by vets treating horses in the United Kingdom (UK) and compare practices with manufacturer datasheets and current guidelines. STUDY

designCross-sectional survey.

methodsAn online questionnaire was distributed using email addresses acquired through professional registration listings and social media, targeting vets who treat horses in the UK. The questionnaire collected demographic data and information regarding vaccination practices and vaccine hesitancy. Descriptive statistical analysis was performed.

resultsQuestionnaires were completed by 304 UK vets working with horses used for leisure (97.4%, n = 296/304), competition (86.2%, n = 262/304), stud-work (47.7%, n = 145/304) and racing (40.5%, n = 123/304). Variation was identified in vaccine protocols for competition and noncompetition horses. Fifty-seven per cent (n = 170/298) of respondents reported variation in advised 'booster' frequency; most commonly (n = 118) advising a 6-monthly vaccination in competition horses and annual vaccination in noncompetition horses. Most common vaccination guidelines volunteered were British Horseracing Authority (68.8%, n = 172/250) and Federation Equestre Internationale (66.4%, n = 166/250). Most vaccination practices were not consistent with datasheet guidance. Only 7.7% (n = 23/300) of respondents complied with datasheet timeframes between the second and third vaccination. Adverse events following vaccination in the previous year were encountered by 66% (n = 199/304) of respondents, representing 2760 adverse events; but only 526 (19.1%) cases were reported to the Veterinary Medicines Directorate. Most common reactions were transient, including stiffness (931), localised swelling (835), lethargy (559) and pyrexia (355). 86.4% respondents reported vaccine hesitancy from horse owners, most commonly due to perception of over-vaccination, cost and concern regarding adverse events. MAIN LIMITATIONS: Potential selection, respondent and recall bias. The recent Equine Influenza (EI) and Equine Herpes Virus (EHV) outbreaks in the UK may have altered responses.

conclusionsCurrent equine vaccination practices, although complying with competition rules, are mostly noncompliant with datasheet guidelines, potentially risking suboptimal immunity.

Indexed as

Horse DiseasesInfluenza, HumanInfluenza VaccinesOrthomyxoviridae InfectionsVaccinesAnimalsCross-Sectional StudiesHorsesHumansUnited KingdomVaccinationInfluenza VaccinesVaccinesadversehesitancyhorseinfluenzaoutbreakUKvaccination

Identifiers

PMID33124070
PMCPMC8451788

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.