Evidence map›Paper›PMID 33123573›Full record

ArticleBioMed research international2020

Acute and Subacute Toxicity Studies of the Aqueous Extract from

Loubna Kharchoufa, Mohamed Bouhrim, Noureddine Bencheikh, Soufiane El Assri, Asmae Amirou, Amal Yamani, Mohammed Choukri, Hassane Mekhfi, Mostafa Elachouri

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 72 citations in OpenAlex.

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  19. The Antitriple Negative Breast cancer Efficacy ofOxidative medicine and cellular longevity · 2021
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  20. Evaluation of Hepatoprotective Activity ofAdvances in pharmacological and pharmaceutical sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Loubna KharchoufaLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, URAC-40, Department of Biology, Faculty of Sciences, Mohammed First University, Oujda, Morocco.
Mohamed BouhrimLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, URAC-40, Department of Biology, Faculty of Sciences, Mohammed First University, Oujda, Morocco.
Noureddine BencheikhLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, URAC-40, Department of Biology, Faculty of Sciences, Mohammed First University, Oujda, Morocco.
Soufiane El AssriBiochemistry Laboratory, Central Laboratory Service-CHU, Mohammed VI, Oujda, Morocco.
Asmae AmirouLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, URAC-40, Department of Biology, Faculty of Sciences, Mohammed First University, Oujda, Morocco.
Amal YamaniLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, URAC-40, Department of Biology, Faculty of Sciences, Mohammed First University, Oujda, Morocco.
Mohammed ChoukriBiochemistry Laboratory, Central Laboratory Service-CHU, Mohammed VI, Oujda, Morocco.
Hassane MekhfiLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, URAC-40, Department of Biology, Faculty of Sciences, Mohammed First University, Oujda, Morocco.
Mostafa ElachouriLaboratory of Bioresources, Biotechnology, Ethnopharmacology and Health, URAC-40, Department of Biology, Faculty of Sciences, Mohammed First University, Oujda, Morocco.ORCID https://orcid.org/0000-0002-4367-7770
Mohamed I University · MACentre Hospitalier Universitaire Mohammed VI · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MATERIALS AND

methodsAcute toxicity test was performed on Swiss albino mice at a single oral dose of 1-10 g/kg for 14 consecutive days. General behavioral adverse effects, mortality, and latency of mortality were determined. In the subacute study, the

resultsAcute toxicity study showed that the oral LD

conclusionOur results indicated low acute toxicity of the aqueous extract of

Indexed as

Administration, OralAnimalsFemaleKidneyLiverMaleMiceOrgan SizePlant ExtractsPlant LeavesRatsRats, WistarRodentiaScopariaToxicity Tests, AcuteWaterPlant ExtractsWater

Identifiers

PMID33123573
PMCPMC7582073
OpenAlexW3092743445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.