Evidence map›Paper›PMID 33123390›Full record

ArticleCase reports in hepatology2020

Development of Hepatocellular Carcinoma in a Patient with Chronic Hepatitis C 21 Years after Achieving a Sustained Virological Response to Interferon Therapy.

Tasuku Hara, Tomoya Ohara, Masashi Taniguchi, Toshiaki Sakai, Kohei Oka, Naoto Iwai, Toshifumi Tsuji, Takashi Okuda, Toshiyuki Komaki, Junichi Sakagami and 1 more

Abstract readCase Reports
In one paragraph

Article in Case reports in hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tasuku HaraDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.ORCID https://orcid.org/0000-0002-1751-6201
Tomoya OharaDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.
Masashi TaniguchiDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.
Toshiaki SakaiDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.
Kohei OkaDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.ORCID https://orcid.org/0000-0002-3193-8531
Naoto IwaiDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.
Toshifumi TsujiDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.
Takashi OkudaDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.
Toshiyuki KomakiDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.
Junichi SakagamiDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.
Keizo KagawaDepartment of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Atsunaka-chou 231, Fukuchiyama, Kyoto 620-8505, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 77-year-old man with chronic hepatitis C (CH-C) infection, who achieved a sustained virological response (SVR) to interferon (IFN) therapy, was followed up regularly. Before IFN therapy, he did not have metabolic diseases, and the histological diagnosis of his chronic hepatitis was stage-3 fibrosis. After achieving SVR, the fibrosis-4 (FIB-4) index level dropped once but gradually increased. 21 years after SVR, hepatocellular carcinoma (HCC) was diagnosed by dynamic computed tomography. The HCC was 12 mm in diameter. The HCC was treated with radiofrequency ablation. CH-C patients with advanced fibrosis require long-term follow-up, even after achieving SVR.

Identifiers

PMID33123390
PMCPMC7582091

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.