Evidence map›Paper›PMID 33123363›Full record

ArticleClinical kidney journal2020

Regulation of urinary calcium excretion by vasopressin.

Pietro Anastasio, Francesco Trepiccione, Natale Gaspare De Santo, Giovambattista Capasso, Davide Viggiano, Giovanna Capolongo

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Pietro AnastasioDepartment of Translational Medical Sciences, University of Campania 'L.Vanvitelli', Naples, Italy.
Francesco TrepiccioneDepartment of Translational Medical Sciences, University of Campania 'L.Vanvitelli', Naples, Italy.
Natale Gaspare De SantoProfessor Emeritus, University of Campania 'L.Vanvitelli', Naples, Italy.
Giovambattista CapassoDepartment of Translational Medical Sciences, University of Campania 'L.Vanvitelli', Naples, Italy.ORCID 0000-0003-3469-8614
Davide ViggianoDepartment of Translational Medical Sciences, University of Campania 'L.Vanvitelli', Naples, Italy.ORCID 0000-0002-2425-6057
Giovanna CapolongoDepartment of Translational Medical Sciences, University of Campania 'L.Vanvitelli', Naples, Italy.
University of Campania "Luigi Vanvitelli" · ITUniversity of Molise · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe antidiuretic hormone (ADH) or arginine vasopressin (AVP) regulates the body's water balance. Recently, modifications in AVP levels have been related to osteoporosis during ageing and microgravity/bed rest. Therefore the present study was devised to assess whether the absence of AVP, as in patients with central diabetes insipidus (CDI), modulates renal calcium excretion.

methodsWe retrospectively analysed data from 12 patients with CDI with measured 24-h urinary excretion levels of calcium. Data were available at the moment of the diagnosis when patients were drug-free and after therapy with dDAVP, an analog of AVP. Hypercalciuria was defined as 24-h urinary Ca

resultsUntreated CDI patients had a daily urinary Ca

conclusionsPatients with CDI show hypercalciuria even though urine is more diluted than normal controls, and dDAVP reverses this effect. These data support the intriguing relationship between AVP and osteoporosis in ageing and microgravity/bed rest.

Indexed as

ageingAVPcalciuriadiabetes insipiduseGFR

Identifiers

PMID33123363
PMCPMC7577769
OpenAlexW3094254215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.