Evidence map›Paper›PMID 33123360›Full record

ArticleClinical kidney journal2020

A clinical predictive model of renal injury in children with isolated antenatal hydronephrosis.

Fernanda P Costa, Ana C Simões E Silva, Robert H Mak, Joachim H Ix, Mariana A Vasconcelos, Cristiane S Dias, Carolina C Fonseca, Maria Christina L Oliveira, Eduardo A Oliveira

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical kidney journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Antenatally detected urinary tract dilatation: long-term outcome.Pediatric nephrology (Berlin, Germany) · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Fernanda P CostaPediatric Nephrourology Division, Department of Pediatrics, National Institute of Science and Technology of Molecular Medicine, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Ana C Simões E SilvaPediatric Nephrourology Division, Department of Pediatrics, National Institute of Science and Technology of Molecular Medicine, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0001-9222-3882
Robert H MakDivision of Pediatric Nephrology, Rady Children's Hospital San Diego, University of California, San Diego, San Diego, CA, USA.
Joachim H IxDivision of Nephrology-Hypertension, University of California, San Diego, San Diego, CA, USA.
Mariana A VasconcelosPediatric Nephrourology Division, Department of Pediatrics, National Institute of Science and Technology of Molecular Medicine, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Cristiane S DiasPediatric Nephrourology Division, Department of Pediatrics, National Institute of Science and Technology of Molecular Medicine, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Carolina C FonsecaPediatric Nephrourology Division, Department of Pediatrics, National Institute of Science and Technology of Molecular Medicine, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Maria Christina L OliveiraPediatric Nephrourology Division, Department of Pediatrics, National Institute of Science and Technology of Molecular Medicine, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Eduardo A OliveiraPediatric Nephrourology Division, Department of Pediatrics, National Institute of Science and Technology of Molecular Medicine, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0002-5642-7164
Universidade Federal de Minas Gerais · BRUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntenatal hydronephrosis (ANH) affects ∼1-5% of pregnancies. The aim of this study was to develop a clinical prediction model of renal injury in a large cohort of infants with isolated ANH.

methodsThis is a longitudinal cohort study of 447 infants with ANH admitted since birth between 1989 and 2015 at a tertiary care center. The primary endpoint was time until the occurrence of a composite event of renal injury, which includes proteinuria, hypertension and chronic kidney disease (CKD). A predictive model was developed using a Cox proportional hazards model and evaluated by

resultsRenal pelvic dilatation (RPD) was classified into two groups [Grades 1-2 (

conclusionOur findings indicate an uneventful clinical course for patients with Society for Fetal Urology (SFU) Grades 1-2 ANH. Conversely, for infants with SFU Grades 3-4 ANH, our prediction model enabled the identification of a subgroup of patients with increased risk of renal injury over time.

Indexed as

antenatal hydronephrosischronic kidney diseaseclinical prediction modelhypertensionproteinuriarenal injuryurinary tract infection

Identifiers

PMID33123360
PMCPMC7577777
OpenAlexW2969445068

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.