Evidence map›Paper›PMID 33123267›Full record

ArticleJournal of Cancer2020

High expression of CD34 and α6-integrin contributes to the cancer-initiating cell behaviour in ultraviolet-induced mouse skin squamous cell carcinoma.

Hengning Ke, YvYing Yang, Yuan Lin, Li Liu, Jianmin Sun, Ramin Massoumi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hengning KeHubei AIDS Clinical Training Center, Department of Infectious Disease, Zhongnan Hospital, Wuhan University, Wuhan, P.R. China.
YvYing YangHubei AIDS Clinical Training Center, Department of Infectious Disease, Zhongnan Hospital, Wuhan University, Wuhan, P.R. China.
Yuan LinSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan, P.R. China.
Li LiuCancer Research Institute, General Hospital, Ningxia Medical University, Yinchuan, P.R. China.
Jianmin SunSchool of Basic Medical Sciences, Ningxia Medical University, Yinchuan, P.R. China.
Ramin MassoumiDepartment of Laboratory Medicine, Translational Cancer Research, Lund University, Medicon Village, Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Squamous cell carcinoma caused by ultraviolet light exposure represents over 40% of all malignant diseases. It is one of the most commonly found human tumours. Tumour mass within squamous cell carcinoma consists of various cell types, including cancer-initiating cells that are responsible for tumour progression, metastasis and chemoresistance and implicated in clinical relapse. In the present study, we aimed to characterise whether the cell population with high CD34 and α6-integrin expression behave as cancer-initiating cells within ultraviolet-induced squamous cell carcinoma in mouse skin. CD34

Indexed as

CD34squamous cell carcinomaUV-Bα6-integrin

Identifiers

PMID33123267
PMCPMC7592010

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.