ArticleExperimental and therapeutic medicine2020
Current practices in haemophilic patients undergoing orthopedic surgery - a systematic review.
Article in Experimental and therapeutic medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Serological Parameters and Vascular Investigation for a Better Assessment in DVT during Pregnancy-A Systematic Review.Medicina (Kaunas, Lithuania) · 2021Pooled it
- Preoperative Coagulation Markers and Clinical Predictors of Transfusion Requirement in Patients Undergoing Total Knee or Hip Arthroplasty: A Single-Center Retrospective Study.Medical sciences (Basel, Switzerland) · 2025Article
- Biomarkers Involved in the Pathogenesis of Hemophilic Arthropathy.International journal of molecular sciences · 2024Review
- The Association between Bleeding Disorders and Postoperative Complications Following Operative Treatment of Distal Radius Fracture.Journal of wrist surgery · 2023Article
- Translation of nanotechnology-based implants for orthopedic applications: current barriers and future perspective.Frontiers in bioengineering and biotechnology · 2023Review
- Hemoperitoneum as a Life-Threatening Complication of an Acute Cholecystitis in a Patient with Hemophilia A with Inhibitors: A Case Report.Healthcare (Basel, Switzerland) · 2022Article
- Hereditary Thrombophilia in the Era of COVID-19.Healthcare (Basel, Switzerland) · 2022Review
- Omega plate for the treatment of acetabular fractures involving the quadrilateral plate.Experimental and therapeutic medicine · 2021Article
- Orthopedic surgery in hemophilic patients with musculoskeletal disorders: A systematic review.Experimental and therapeutic medicine · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Haemophilia is an inherited disease that requires a different approach in order to evaluate, monitor and treat patients. Despite the great advances in therapeutic agents that have emerged, reports on the impact of monitoring outcomes on treatment decisions are rarely presented. Haemophilia A and haemophilia B are inherited bleeding disorders caused by deficiencies in blood clotting factor proteins. A systematic review was performed to identify literature reports on the current practices in haemophilic patients undergoing orthopedic surgery. The best therapy for haemophilic patients consists in performing primary prophylaxis to prevent joint bleeding and other complications. Besides the primary prophylaxis, thromboprophylaxis is used to prevent venous thrombosis in patients with hemophilia who undergo surgical orthopedic procedures. Further research is needed to better manage the pharmacologic approaches in haemophilic patients undergoing orthopedic surgery. Although patients with haemophilia present low risk for thromboembolic complications, such events have been reported in surgical procedures. The recommendations in patients with haemophilia are considerably variable in the current guidelines and clinical practice. The best therapy for haemophilic patients consists in performing primary prophylaxis to prevent joint bleeding and other complications.
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