Evidence map›Paper›PMID 33123155›Full record

ArticleFrontiers in immunology2020

Evolutionarily Selected Overexpression of the Cytokine BAFF Enhances Mucosal Immune Response Against

Valeria Lodde, Matteo Floris, Isabel Beerman, Rachel Munk, Rajan Guha, Maristella Steri, Valeria Orrù, Kotb Abdelmohsen, Peter D Crompton, Myriam Gorospe and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Circular RNAs in Immune-Related Diseases.Advances in experimental medicine and biology · 2025
    Review
  3. Article
  4. Review
  5. Non-coding RNAs in malaria infection.Wiley interdisciplinary reviews. RNA · 2022
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Valeria LoddeDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Matteo FlorisDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Isabel BeermanEpigenetics and Stem Cell Unit, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States.
Rachel MunkLaboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, United States.
Rajan GuhaMalaria Infection Biology and Immunity Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States.
Maristella SteriIstituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Italy.
Valeria OrrùIstituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Italy.
Kotb AbdelmohsenLaboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, United States.
Peter D CromptonMalaria Infection Biology and Immunity Section, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States.
Myriam GorospeLaboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, United States.
Maria Laura IddaIstituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche (CNR), Monserrato, Italy.
Francesco CuccaDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Institute of Genetic and Biomedical Research · ITInstitute on Aging · USNational Institute of Allergy and Infectious Diseases · USUniversity of Sassari · ITNational Institute on Aging · USNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have previously shown that a variant of the

Indexed as

Evolution, MolecularImmunity, MucosalAdultAgedAged, 80 and overB-Cell Activating FactorB-LymphocytesCells, CulturedErythrocytesFemaleGenetic FitnessGenotypeHost-Parasite InteractionsHumansItalyMalaria, FalciparumB-Cell Activating FactorTNFSF13B protein, humanBAFFevolutiongene regulationimmune regulationmalaria

Identifiers

PMID33123155
PMCPMC7573158
OpenAlexW3092250849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.