ReviewFrontiers in immunology2020
Immunoglobulins, Mucosal Immunity and Vaccination in Teleost Fish.
Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 248 citations in OpenAlex.
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- The Invisible Balance: How Prebiotics and Probiotics Can Support Fish Health and Development.Life (Basel, Switzerland) · 2026Review
- Zinc alleviates arsenic-induced muscle injury in common carp through modulation of oxidative stress and related signaling pathways.Fish physiology and biochemistry · 2026Article
- Nanotechnology-Based Immunostimulants in Aquaculture: Mechanisms, Advances and Practical Applications.Veterinary medicine and science · 2026Review
- Transcriptomic and Proteomic Insights into Mucosal Immune Responses of Asian Seabass (International journal of molecular sciences · 2026Article
- Chromosome-scale genome of European anchovy (Engraulis encrasicolus L., 1758) and comparative genomics uncover clupeid-specific immune gene expansions.DNA research : an international journal for rapid publication of reports on genes and genomes · 2026Article
- Immune-pathological response induced by Saprolegnia parasitica in Pangasianodon hypophthalmus and assessment of clinical efficacy of clotrimazole.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Biophytum sensitivum: a promising herbal diet supplement for enhancing growth, immune response, antioxidant status, and disease resistance in Nile tilapia (Oreochromis niloticus).Fish physiology and biochemistry · 2026Article
- Genomic Insights into Genetic Diversity of Coilia nasus Across Wild Ecotypes and Farmed Populations in China.Marine biotechnology (New York, N.Y.) · 2026Article
- Novel function of Teleost skin: Antigen excretion across the epidermis mediated by secretory IgMFundamental research · 2026Article
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- Effects ofVaccines · 2026Article
- Gut T cell-microbiota crosstalk orchestrates antibacterial immunity and mucosal homeostasis in teleost.Microbiome · 2026Article
- Assessing the effect of Bacillus rugosus NM007 as a novel probiotic strain on growth performance, hemato-biochemical profile, immune response, digestive enzymes and intestinal histomorphology of Nile tilapia (Oreochromis niloticus).World journal of microbiology & biotechnology · 2026Article
- p53 regulates early mucosal immunity via antigen presentation in zebrafish intestine post-SVCV vaccination.Cell communication and signaling : CCS · 2026Article
- Effect of substituting fishmeal with black soldier fly and mealworm larvae meal on nutrient digestibility, body and mineral composition ofOpen veterinary journal · 2026Article
- INHAND: Non-proliferative and proliferative lesions of fish - Chapter 5. Fish hematolymphoid system.Journal of toxicologic pathology · 2026Article
- Antibiotic use in Chilean salmon aquaculture: antimicrobial resistance, sustainability, and One Health implications.Frontiers in microbiology · 2026Review
- Characterization and Vaccine Development ofVaccines · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to direct contact with aquatic environment, mucosal surfaces of teleost fish are continuously exposed to a vast number of pathogens and also inhabited by high densities of commensal microbiota. The B cells and immunoglobulins within the teleost mucosa-associated lymphoid tissues (MALTs) play key roles in local mucosal adaptive immune responses. So far, three Ig isotypes (i.e., IgM, IgD, and IgT/Z) have been identified from the genomic sequences of different teleost fish species. Moreover, teleost Igs have been reported to elicit mammalian-like mucosal immune response in six MALTs: gut-associated lymphoid tissue (GALT), skin-associated lymphoid tissue (SALT), gill-associated lymphoid tissue (GIALT), nasal-associated lymphoid tissue (NALT), and the recently discovered buccal and pharyngeal MALTs. Critically, analogous to mammalian IgA, teleost IgT represents the most ancient Ab class specialized in mucosal immunity and plays indispensable roles in the clearance of mucosal pathogens and the maintenance of microbiota homeostasis. Given these, this review summarizes the current findings on teleost Igs, MALTs, and their immune responses to pathogenic infection, vaccination and commensal microbiota, with the purpose of facilitating future evaluation and rational design of fish vaccines.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.