Evidence map›Paper›PMID 33123133›Full record

ArticleFrontiers in immunology2020

Artificial Intelligence Applied to

Nicola Cotugno, Veronica Santilli, Giuseppe Rubens Pascucci, Emma Concetta Manno, Lesley De Armas, Suresh Pallikkuth, Annalisa Deodati, Donato Amodio, Paola Zangari, Sonia Zicari and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Large language models for bioinformatics.Quantitative biology (Beijing, China) · 2026
    Review
  5. Article
  6. Article
  7. Towards personalized vaccines.Frontiers in immunology · 2024
    Review
  8. Review
  9. Virological and immunological features of SARS-COV-2 infected children with distinct symptomatology.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Nicola CotugnoAcademic Department of Pediatrics (DPUO), Research Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, Rome, Italy.
Veronica SantilliAcademic Department of Pediatrics (DPUO), Research Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, Rome, Italy.
Giuseppe Rubens PascucciAcademic Department of Pediatrics (DPUO), Research Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, Rome, Italy.
Emma Concetta MannoAcademic Department of Pediatrics (DPUO), Research Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, Rome, Italy.
Lesley De ArmasMiami Center for AIDS Research, Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, United States.
Suresh PallikkuthMiami Center for AIDS Research, Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, United States.
Annalisa DeodatiAcademic Department of Pediatrics (DPUO), Research Unit of Growth Disorders, Bambino Gesù Children's Hospital, Rome, Italy.
Donato AmodioAcademic Department of Pediatrics (DPUO), Research Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, Rome, Italy.
Paola ZangariAcademic Department of Pediatrics (DPUO), Research Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, Rome, Italy.
Sonia ZicariAcademic Department of Pediatrics (DPUO), Research Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, Rome, Italy.
Alessandra RuggieroAcademic Department of Pediatrics (DPUO), Research Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, Rome, Italy.
Martina FortinBioStat Solutions, Inc., Frederick, MD, United States.
Christina BromleyBioStat Solutions, Inc., Frederick, MD, United States.
Rajendra PahwaMiami Center for AIDS Research, Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, United States.
Paolo RossiAcademic Department of Pediatrics (DPUO), Research Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, Rome, Italy.
Savita PahwaMiami Center for AIDS Research, Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, United States.
Paolo PalmaAcademic Department of Pediatrics (DPUO), Research Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, Rome, Italy.
Bambino Gesù Children's Hospital · ITUniversity of Miami · USUniversity of Rome Tor Vergata · IT

Funding

University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GWENDOLYN Barbara SCOTT · 2007 to 2026
$33.8M
Immunity and HIV persistence in perinatal HIV infectionR01AI127347 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PAHWA, SAVITA · 2016 to 2020
$3.3M
Antibody Responses in HIV and AgingR01AI108472 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PAHWA, SAVITA · 2013 to 2017
$2.9M
NIAID NIH HHS P30 AI073961NIAID NIH HHS R01 AI108472NIAID NIH HHS R01 AI127347
6 · The paper itself

Abstract

The number of patients affected by chronic diseases with special vaccination needs is burgeoning. In this scenario, predictive markers of immunogenicity, as well as signatures of immune responses are typically missing even though it would especially improve the identification of personalized immunization practices in these populations. We aimed to develop a predictive score of immunogenicity to Influenza Trivalent Inactivated Vaccination (TIV) by applying deep machine learning algorithms using transcriptional data from sort-purified lymphocyte subsets after

Indexed as

Artificial IntelligenceGene Expression ProfilingImmunogenicity, VaccineTranscriptomeChildCoinfectionComputational BiologyHemagglutination Inhibition TestsHIV InfectionsHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanInfluenza VaccinesPrognosisReproducibility of ResultsVaccinationInfluenza VaccinesVaccines, Inactivatedartificial intelligencedeep learninggene expressionHIVinfluenza vaccinepredictive biomarkersvaccinomics

Identifiers

PMID33123133
PMCPMC7569088
OpenAlexW3091793466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.