Evidence map›Paper›PMID 33123132›Full record

ArticleFrontiers in immunology2020

Polyunsaturated Fatty Acids Influence LPS-Induced Inflammation of Fish Macrophages Through Differential Modulation of Pathogen Recognition and p38 MAPK/NF-κB Signaling.

Qingfei Li, Kun Cui, Mengjiao Wu, Dan Xu, Kangsen Mai, Qinghui Ai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

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  15. Protective Effects ofInternational journal of molecular sciences · 2021
    Article
  16. Early Life Intervention Using ProbioticFrontiers in immunology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qingfei LiKey Laboratory of Aquaculture Nutrition and Feed (Ministry of Agriculture) & Key Laboratory of Mariculture (Ministry of Education), College of Fisheries, Ocean University of China, Qingdao, China.
Kun CuiKey Laboratory of Aquaculture Nutrition and Feed (Ministry of Agriculture) & Key Laboratory of Mariculture (Ministry of Education), College of Fisheries, Ocean University of China, Qingdao, China.
Mengjiao WuKey Laboratory of Aquaculture Nutrition and Feed (Ministry of Agriculture) & Key Laboratory of Mariculture (Ministry of Education), College of Fisheries, Ocean University of China, Qingdao, China.
Dan XuKey Laboratory of Aquaculture Nutrition and Feed (Ministry of Agriculture) & Key Laboratory of Mariculture (Ministry of Education), College of Fisheries, Ocean University of China, Qingdao, China.
Kangsen MaiKey Laboratory of Aquaculture Nutrition and Feed (Ministry of Agriculture) & Key Laboratory of Mariculture (Ministry of Education), College of Fisheries, Ocean University of China, Qingdao, China.
Qinghui AiKey Laboratory of Aquaculture Nutrition and Feed (Ministry of Agriculture) & Key Laboratory of Mariculture (Ministry of Education), College of Fisheries, Ocean University of China, Qingdao, China.
Ocean University of China · CNQingdao National Laboratory for Marine Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyunsaturated fatty acids (PUFAs) not only serve as essential nutrients but also function as modulators of the immune response in marine fish. However, their immunomodulatory mechanism is poorly understood given that the underlying regulation of the innate immune response in fish has not been fully elucidated. Hence, study of the innate immunity of fish could help elucidate the mechanism by which PUFAs affect the fish immune response. Here, we used combined transcriptome analysis and

Indexed as

AnimalsComputational BiologyFish DiseasesGene Expression ProfilingGene Expression RegulationGene OntologyHost-Pathogen InteractionsInflammationInterleukin-1betaLipopolysaccharidesMacrophagesMolecular Sequence AnnotationNF-kappa Bp38 Mitogen-Activated Protein KinasesPromoter Regions, GeneticProtein BindingInterleukin-1betaLipopolysaccharidesNF-kappa Bp38 Mitogen-Activated Protein Kinasesimmunomodulatory effectsinflammatory responseslarge yellow croakerLPSpolyunsaturated fatty acids (PUFAs)signaling transduction

Identifiers

PMID33123132
PMCPMC7572853
OpenAlexW3092601502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.