Evidence map›Paper›PMID 33123083›Full record

ArticleFrontiers in endocrinology2020

The Association Between Obesity and Risk of Acute Kidney Injury After Cardiac Surgery.

Ning Shi, Kang Liu, Yuanming Fan, Lulu Yang, Song Zhang, Xu Li, Hanzhang Wu, Meiyuan Li, Huijuan Mao, Xueqiang Xu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Observational
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  8. Partial upper sternotomyWorld journal of cardiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ning ShiClinical Metabolomics Center, China Pharmaceutical University, Nanjing, China.
Kang LiuDepartment of Nephrology, Jiangsu Province Hospital, Nanjing, China.
Yuanming FanClinical Metabolomics Center, China Pharmaceutical University, Nanjing, China.
Lulu YangClinical Metabolomics Center, China Pharmaceutical University, Nanjing, China.
Song ZhangClinical Metabolomics Center, China Pharmaceutical University, Nanjing, China.
Xu LiClinical Metabolomics Center, China Pharmaceutical University, Nanjing, China.
Hanzhang WuDepartment of Nephrology, Jiangsu Province Hospital, Nanjing, China.
Meiyuan LiDepartment of Nephrology, Jiangsu Province Hospital, Nanjing, China.
Huijuan MaoDepartment of Nephrology, Jiangsu Province Hospital, Nanjing, China.
Xueqiang XuDepartment of Nephrology, Jiangsu Province Hospital, Nanjing, China.
Shi-Ping MaState Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.
Pingxi XiaoDepartment of Cardiology, The Affiliated Sir Run Run Hospital of Nanjing Medical University, Nanjing, China.
Shujun JiangClinical Metabolomics Center, China Pharmaceutical University, Nanjing, China.
China Pharmaceutical University · CNJiangsu Province Hospital · CNNanjing Medical University · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine the relationship between obesity and the risk of AKI after cardiac surgery (CS-AKI) in a cohort study. Methods: A total of 1,601 patients undergoing cardiac surgery were collected and their incidence of CS-AKI was recorded. They were divided into underweight, normal weight, overweight, and obese groups. Logistic regression was used to estimate the association between BMI (body mass index) and CS-AKI risk. Then, a meta-analysis of published cohort studies was conducted to confirm this result using PubMed and Embase databases. Results: A significant association was observed in this independent cohort after adjusting age, gender, hypertension and New York Heart Association classification (NYHA) class. Compared with normal BMI group (18.5 ≤ BMI < 24.0), the individuals with aberrant BMI level had an increased AKI risk (OR: 1.68, 95% CI: 1.01-2.78) for BMI < 18.5 group and (OR: 1.43, 95% CI: 0.96-2.15) for BMI ≥ 28.0. Interestingly, the U-shape curve showed the CS-AKI risk reduced with the increasing of BMI when BMI ≤ 24.0. As BMI increases with BMI > 24.0, the risk of developing CS-AKI increased significantly. In the confirmed meta-analysis, compared with normal weight, overweight group with cardiac surgery had higher AKI risk (OR: 1.28, 95% CI: 1.16-1.41, Conclusion: In conclusion, the results suggested that abnormal BMI was a risk factor for CS-AKI independently.

Indexed as

Acute Kidney InjuryAdultAgedBody Mass IndexCardiac Surgical ProceduresFemaleHumansIncidenceMaleMiddle AgedObesityPostoperative ComplicationsRiskacute kidney injurybody mass indexcardiac surgerycreatinineobesity

Identifiers

PMID33123083
PMCPMC7573233
OpenAlexW3092458360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.