Evidence map›Paper›PMID 33123070›Full record

ArticleFrontiers in neurology2020

Brain Amyloid Burden and Resting-State Functional Connectivity in Late Middle-Aged Hispanics.

Mouna Tahmi, Brady Rippon, Priya Palta, Luisa Soto, Fernando Ceballos, Michelle Pardo, Greysi Sherwood, Gabriela Hernandez, Rodolfo Arevalo, Hengda He and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 1 country.

Mouna TahmiDepartment of Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Brady RipponDepartment of Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Priya PaltaDepartment of Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Luisa SotoDepartment of Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Fernando CeballosDepartment of Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Michelle PardoDepartment of Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Greysi SherwoodDepartment of Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Gabriela HernandezDepartment of Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Rodolfo ArevaloDepartment of Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Hengda HeDepartment of Biomedical Engineering, Columbia University, New York, NY, United States.
Amirreza SedaghatDepartment of Biomedical Engineering, Columbia University, New York, NY, United States.
Soroush ArabshahiDepartment of Biomedical Engineering, Columbia University, New York, NY, United States.
Jeanne TeresiResearch Division, Hebrew Home in Riverdale, Bronx, NY, United States.
Herman MorenoDepartments of Neurology and Physiology/Pharmacology, The Robert F. Furchgott Center for Neural and Behavioral Science, SUNY Downstate Medical Center, New York, NY, United States.
Adam M BrickmanDepartment of Neurology, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Qolamreza R RazlighiDepartment of Radiology, Weill Cornell Medicine, New York, NY, United States.
José A LuchsingerDepartment of Medicine, College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, United States.
Columbia University · USColumbia University Irving Medical Center · USHebrew Home · USKings County Hospital Center · USWeill Cornell Medicine · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Metformin in Alzheimer's dementia Prevention (MAP)R01AG062624 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HANLEY, DANIEL F, LUCHSINGER, JOSE ALEJANDRO · 2019 to 2025
$37.8M
Residing in the Community with Dementia at the End of Life: Understanding Hospice Use and Residential SettingP30AG028741 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ORNA INTRATOR · 2010 to 2026
$21.9M
Diabetes Status and Brain Amyloid in Middle Aged HispanicsR01AG050440 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LUCHSINGER, JOSE ALEJANDRO · 2015 to 2025
$21.9M
Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid · 2003 to 2026
$15.2M
Interdisciplinary Research to Understand the Interplay of Diabetes, Cerebrovascular disease and Alzheimers diseaseRF1AG051556 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BRICKMAN, ADAM M, LUCHSINGER, JOSE ALEJANDRO · 2015 to 2019
$9.7M
Research Education CoreP30AG059303 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ADAM M BRICKMAN, Jennifer Jaie Manly · 2018 to 2026
$6.0M
Midcareer Award for Research in Dementia Risk Factors and PreventionK24AG045334 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Jose Alejandro Luchsinger · 2016 to 2026
$1.5M
Physical Activity and Preservation of Cognitive FunctionR00AG052830 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI PALTA, PRIYA · 2019 to 2021
$1.1M
NCATS NIH HHS UL1 TR001873NIA NIH HHS K24 AG045334NIA NIH HHS P30 AG022845NIA NIH HHS P30 AG028741NIA NIH HHS P30 AG059303NIA NIH HHS R00 AG052830NIA NIH HHS R01 AG050440NIA NIH HHS R01 AG062624NIA NIH HHS RF1 AG051556
6 · The paper itself

Abstract

Non-linear relations of brain amyloid beta (Aβ) with task- based functional connectivity (tbFC) measured with functional magnetic resonance imaging (fMRI) have been reported in late middle age. Our objective was to examine the association between brain Aβ and resting-state functional connectivity (rsFC) in late middle-aged adults. Global brain Aβ burden was ascertained with

Indexed as

Alzheimer's diseaseamyloid betafMRIfunctional connectivityhispanicmiddle-ageRsfMRI

Identifiers

PMID33123070
PMCPMC7573129
OpenAlexW3092512644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.