ReviewJournal of clinical pathology1987
The role of immunocytochemistry in diagnostic pathology.
Review in Journal of clinical pathology, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 83 citations in OpenAlex.
- Review
- Immunohistochemistry as a diagnostic tool in pathology.Bioinformation · 2025Article
- Cancer Stem Cell Marker CD147 Expression in Erosive Oral Lichen Planus Compared to Moderately and Severely Dysplastic Leukoplakia.Reports (MDPI) · 2024Article
- Antigens under cover-The preservation and demasking of selected antigens for successful poststaining immunocytochemistry of effusion, brain smears, and lymph node aspirates.Veterinary clinical pathology · 2019Article
- Heat-induced antigen retrieval for immunohistochemical reactions in routinely processed paraffin sections.Methods in molecular biology (Clifton, N.J.) · 2010Article
- Naltrexone, an opioid receptor antagonist, attenuates liver fibrosis in bile duct ligated rats.Gut · 2006Article
- Differential expression of cytokeratin after orthotopic implantation of newly established human tongue cancer cell lines of defined metastatic ability.The American journal of pathology · 2000Article
- Multiparameter flow cytometric characterization of epidermal cell suspensions prepared from normal and hyperproliferative human skin using an optimized thermolysin-trypsin protocol.Archives of dermatological research · 1996Article
- Production and characterisation of an antimelanoma monoclonal antibody KBA.62 using a new melanoma cell line reactive on paraffin wax embedded sections.Journal of clinical pathology · 1995Article
- CD68 reactivity of non-macrophage derived tumours in cytological specimens.Journal of clinical pathology · 1993Article
- Large cell anaplastic lymphoma: evaluation of immunophenotype on paraffin and frozen sections in comparison with ultrastructural features.Virchows Archiv. A, Pathological anatomy and histopathology · 1991Article
- Immunohistochemical differential diagnosis of granulocytic sarcomas and malignant lymphomas on formalin-fixed material.Virchows Archiv. A, Pathological anatomy and histopathology · 1990Article
- Use of APAAP technique on paraffin wax embedded bone marrow trephines.Journal of clinical pathology · 1989Article
- Molecule detected in formalin fixed tissue by antibodies MT1, DF-T1, and L60 (Leu-22) corresponds to CD43 antigen.Journal of clinical pathology · 1989Article
- Simultaneous application of in situ DNA hybridization and immunohistochemistry on one tissue section.The Histochemical journal · 1989Article
- Malignant lymphomas of the nasal cavity and paranasal sinuses.Virchows Archiv. A, Pathological anatomy and histopathology · 1989Article
- Monoclonal antibodies for clinical applications. Patents and literature.Applied biochemistry and biotechnology · 1988Article
- Role of immunocytochemistry in diagnostic pathology: information from necrotic tissue.Journal of clinical pathology · 1988Article
- Antibody mediated targeting of radioisotopes, drugs and toxins in diagnosis and treatment.Indian journal of pediatricsReview
- Comparative assessment between objective and subjective methods in slides stained by immunohistochemistry.Brazilian journal of otorhinolaryngologyArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review suggests that immunocytochemistry in diagnostic pathology can be performed using relatively small panels of antibodies and that it should be reserved for situations in which, for one reason or another, the pathologist cannot exert his or her conventional diagnostic skills. Examples include the diagnosis of tumours the true nature of which is uncertain because of anaplasia or poor morphological preservation; the demonstration of small numbers of cells which are otherwise too rare to be recognised in conventionally stained preparations; and the immunophenotyping of non-Hodgkin's lymphomas. Recently progress has been made in the context of non-Hodgkin's lymphomas by the development of monoclonal antibodies that detect T and B cell associated markers in paraffin wax sections. Most of these reagents, however, recognise either lineage associated (but not lineage specific) variants of the leucocyte common antigen CD45, or antigens that are poorly characterised. A recent promising development has therefore been the demonstration that polyclonal antisera raised against the CD3/T3 T cell specific marker (purified by affinity chromatography) are suitable for staining T cells in paraffin sections. This approach will hopefully enable antibodies to be produced which react with other well defined white cell associated markers in routine biopsy material.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.