Evidence map›Paper›PMID 33122798›Full record

ArticleScientific reports2020

Eco friendly silver nanoparticles synthesis by Brassica oleracea and its antibacterial, anticancer and antioxidant properties.

Sabah Ansar, Hajera Tabassum, Norah S M Aladwan, Mir Naiman Ali, Basmah Almaarik, Salma AlMahrouqi, Manal Abudawood, Naheed Banu, Roua Alsubki

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 178 citations in OpenAlex.

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  19. Antibacterial and antioxidant activity of gold and silver nanoparticles in dextran-polyacrylamide copolymers.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
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  20. Green Synthesis of Novel Silver Nanoparticles UsingInternational journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Sabah AnsarDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia. sabahansar16@gmail.com.
Hajera TabassumDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.
Norah S M AladwanDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.
Mir Naiman AliMicrobiology Section, Riyadh Municipality Central Area Labs, Riyadh, Saudi Arabia.
Basmah AlmaarikDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh, 11433, Saudi Arabia.
Salma AlMahrouqiDepartment of Nutrition and Dietetics, Sultan Qaboos University Hospital, Seeb, Oman.
Manal AbudawoodChair of Medical and Molecular Genetics Research, Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Naheed BanuDepartment of Physical Therapy, College of Medical Rehabilitation, Qassim University, Buraydah, Saudi Arabia.
Roua AlsubkiChair of Medical and Molecular Genetics Research, Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
King Saud University · SAQassim University · SARiyadh Armed Forces Hospital · SASultan Qaboos University Hospital · OM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Production of environmentally amenable silver nanoparticles (AgNPs) has garnered the interest of the scientific community owing to their broad application primarily in the field of optronics, sensing and extensively in pharmaceuticals as promising antioxidant, antimicrobial and anticancer agents. The current study emphases on production of ecofriendly silver nanoparticles from Brassica oleracea (BO) and investigated their antibacterial, anticancer and antioxidant activity. The characteristics of synthesized BO-AgNPs were studied by ultraviolet-visible spectroscopy, particle size analysis, electro kinetic/zeta potential analysis, and Transmission electron microscope (TEM). A distinctive absorption maximum at 400 nm confirmed the formation of BO-AgNPs and data on TEM analysis have shown that the synthesized nanoparticles were predominantly spherical in shape. The BO-AgNPs obtained were assessed for antibacterial, antioxidant, and cytotoxic ability in MCF-7 cells. The antibacterial activity expressed was maximum against Staphylococcus epidermidis (Gram positive) and Pseudomonas aeruginosa (Gram negative) with DIZ of 14.33 ± 0.57 and 12.0 ± 0.20 mm respectively. Furthermore, the ability of the synthesized green nanoparticles to scavenge free radicals revealed a strong antioxidant activity. The cytotoxicity increased proportionately with increasing concentration of the green synthesized BO-AgNPs with maximum effect at 100 μg/ml and IC50 of 55 μg/ml. In conclusion, the data obtained in the study is reflective of the role of BO-AgNPs as potential and promising antimicrobial agent against bacterial infections and potential anticancer agent in cancer therapy.

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsAntioxidantsBrassicaCell Line, TumorGreen Chemistry TechnologyHumansMCF-7 CellsMetal NanoparticlesMicrobial Sensitivity TestsPlant ExtractsSilverAnti-Bacterial AgentsAntineoplastic AgentsAntioxidantsPlant ExtractsSilver

Identifiers

PMID33122798
PMCPMC7596502
OpenAlexW3096776276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.