Evidence map›Paper›PMID 33122769›Full record

ArticleScientific reports2020

ERgene: Python library for screening endogenous reference genes.

Zehua Zeng, Yuzhe Xiong, Wenhuan Guo, Hongwu Du

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zehua Zeng112 Lab, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing, 100083, China.
Yuzhe Xiong112 Lab, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing, 100083, China.
Wenhuan Guo112 Lab, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing, 100083, China.
Hongwu Du112 Lab, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing, 100083, China. hongwudu@ustb.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In gene expression analysis, sample differences and experimental operation differences are common, but sometimes, these differences will cause serious errors to the results or even make the results meaningless. Finding suitable internal reference genes efficiently to eliminate errors is a challenge. Aside from the need for high efficiency, there is no package for screening endogenous genes available in Python. Here, we introduce ERgene, a Python library for screening endogenous reference genes. It has extremely high computational efficiency and simple operation steps. The principle is based on the inverse process of the internal reference method, and the robust matrix block operation makes the selection of internal reference genes faster than any other method.

Indexed as

AlgorithmsAnimalsGene Expression ProfilingGene LibraryGenetic TestingHumansSoftware

Identifiers

PMID33122769
PMCPMC7596506

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.