Evidence map›Paper›PMID 33122748›Full record

ArticleScientific reports2020

Variation in the susceptibility of urban Aedes mosquitoes infected with a densovirus.

Aurélie Perrin, Anne-Sophie Gosselin-Grenet, Marie Rossignol, Carole Ginibre, Bethsabée Scheid, Christophe Lagneau, Fabrice Chandre, Thierry Baldet, Mylène Ogliastro, Jérémy Bouyer

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

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  14. Symbiotic Interactions Between Mosquitoes and Mosquito Viruses.Frontiers in cellular and infection microbiology · 2021
    Review
  15. Intracellular Interactions Between Arboviruses andFrontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Aurélie PerrinUMR MIVEGEC, CNRS, IRD, Univ Montpellier, Montpellier, France. aurelie.perrin@ird.fr.
Anne-Sophie Gosselin-GrenetUMR DGIMI, INRAE, Univ Montpellier, Montpellier, France.
Marie RossignolUMR MIVEGEC, CNRS, IRD, Univ Montpellier, Montpellier, France.
Carole GinibreUMR MIVEGEC, CNRS, IRD, Univ Montpellier, Montpellier, France.
Bethsabée ScheidUMR MIVEGEC, CNRS, IRD, Univ Montpellier, Montpellier, France.
Christophe LagneauEID-med, Entente Interdépartementale pour la Démoustication du littoral méditerranéen, Montpellier, France.
Fabrice ChandreUMR MIVEGEC, CNRS, IRD, Univ Montpellier, Montpellier, France.
Thierry BaldetASTRE, Cirad, INRAE, Univ Montpellier, Montpellier, France.
Mylène OgliastroUMR DGIMI, INRAE, Univ Montpellier, Montpellier, France.
Jérémy BouyerASTRE, Cirad, INRAE, Univ Montpellier, Montpellier, France.
Centre de Coopération Internationale en Recherche Agronomique pour le Développement · FRInstitut de Recherche pour le Développement · FRMaladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle · FRDiversité, génomes et interactions micro-organismes-insectes · FRInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement · FRUniversité de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urban Aedes mosquitoes are vectors of many viruses affecting human health such as dengue, chikungunya and Zika viruses. Insecticide resistance and environmental toxicity risks hamper the effectiveness of chemical control against these mosquito vectors. Alternative control methods, such as the use of mosquito-specific entomopathogenic viruses should be explored. Numerous studies have focused on evaluating the potential of different densoviruses species as biological control agents. However, knowledge on the extent of inter- and intra-specific variations in the susceptibility of Aedes mosquitoes to infection by different densoviruses remains insufficient. In this study, we compared infection and mortality rates induced by the Aedes albopictus densovirus 2 in different strains of Aedes albopictus and Aedes aegypti mosquitoes. The two Aedes species were different in terms of susceptibility to viral infection. Under laboratory conditions, Aedes albopictus densovirus 2 appeared more virulent for the different strains of Aedes aegypti tested than for those of Aedes albopictus. In addition, we also found significant intra-specific variation in infection and mortality rates. Thus, although even if Aedes albopictus densoviruses could be powerful biocontrol agents used in the management of urban Aedes populations, our results also call into question the use of single viral isolate as biocontrol agents.

Indexed as

AedesAnimalsDensovirusFemaleLarvaMaleViral Load

Identifiers

PMID33122748
PMCPMC7596516
OpenAlexW3094805802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.