Evidence map›Paper›PMID 33122712›Full record

ArticleScientific reports2020

Biorheology of occlusive thrombi formation under high shear: in vitro growth and shrinkage.

Britt J M van Rooij, Gábor Závodszky, Alfons G Hoekstra, David N Ku

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Britt J M van RooijComputational Science Lab, Institute for Informatics, University of Amsterdam, Amsterdam, The Netherlands.
Gábor ZávodszkyComputational Science Lab, Institute for Informatics, University of Amsterdam, Amsterdam, The Netherlands.
Alfons G HoekstraComputational Science Lab, Institute for Informatics, University of Amsterdam, Amsterdam, The Netherlands. a.g.hoekstra@uva.nl.
David N KuGWW School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, USA.
University of Amsterdam · NLGeorgia Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Occlusive thrombi formed under high flow shear rates develop very rapidly in arteries and may lead to myocardial infarction or stroke. Rapid platelet accumulation (RPA) and occlusion of platelet-rich thrombi and clot shrinkage have been studied after flow arrest. However, the influence of margination and shear rate on occlusive clot formation is not fully understood yet. In this study, the influence of flow on the growth and shrinkage of a clot is investigated. Whole blood (WB) and platelet-rich plasma (PRP) were perfused at high shear rates (> 3,000 s

Indexed as

AnimalsBlood CoagulationBlood PlateletsConstriction, PathologicPlatelet AdhesivenessPlatelet AggregationPlatelet-Rich PlasmaStress, MechanicalSwineThrombosis

Identifiers

PMID33122712
PMCPMC7596481
OpenAlexW3096912185

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.