Evidence map›Paper›PMID 33122667›Full record

ArticleScientific reports2020

Hypotensive and antihypertensive effects of an aqueous extract from Guinep fruit (Melicoccus bijugatus Jacq) in rats.

Chukwuemeka R Nwokocha, Alexia Gordon, Javier Palacios, Adrian Paredes, Fredi Cifuentes, Sheena Francis, JeAnn Watson, Rupika Delgoda, Magdalene Nwokocha, Ruby Alexander-Lindo and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Chukwuemeka R NwokochaDepartment of Basic Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, Mona Campus, Kingston 7, Jamaica. chukwuemeka.nwokocha@uwimona.edu.jm.
Alexia GordonDepartment of Basic Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, Mona Campus, Kingston 7, Jamaica.
Javier PalaciosLaboratorio de Bioquímica Aplicada, Departamento Química y Farmacia, Facultad de Ciencias de la Salud, Universidad Arturo Prat, 1110939, Iquique, Chile. clpalaci@unap.cl.
Adrian ParedesDepartamento Química y Farmacia, Facultad de Ciencias Básicas, Universidad de Antofagasta, 1271155, Antofagasta, Chile.
Fredi CifuentesLaboratorio de Fisiología Experimental, Instituto Antofagasta (IA), Universidad de Antofagasta, 1270300, Antofagasta, Chile.
Sheena FrancisNatural Products Institute, Faculty of Science and Technology, The University of the West Indies, Mona, Kingston 7, Jamaica.
JeAnn WatsonNatural Products Institute, Faculty of Science and Technology, The University of the West Indies, Mona, Kingston 7, Jamaica.
Rupika DelgodaNatural Products Institute, Faculty of Science and Technology, The University of the West Indies, Mona, Kingston 7, Jamaica.
Magdalene NwokochaDepartment of Pathology, Faculty of Medical Sciences, University of the West Indies, Mona Campus, Kingston 7, Jamaica.
Ruby Alexander-LindoDepartment of Basic Medical Sciences, Faculty of Medical Sciences, The University of the West Indies, Mona Campus, Kingston 7, Jamaica.
Rory ThompsonDepartment of Pathology, Faculty of Medical Sciences, University of the West Indies, Mona Campus, Kingston 7, Jamaica.
Donna Minott-KatesDepartment of Chemistry, University of the West Indies, Mona, Kingston 7, Jamaica.
Momoh A YakubuDepartment of Environmental and Interdisciplinary Sciences, College of Science, Engineering and Technology, Texas Southern University, Houston, TX, 77004, USA.
University of the West Indies System · JMUniversity of the West Indies · JMUniversity of Antofagasta · CLArturo Prat University · CLTexas Southern University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melicoccus bijugatus Jacq (Mb) has been reported to have cardiovascular modulatory effects. In this study, we evaluated the antihypertensive effects and mechanism of action of Mb on N

Indexed as

AnimalsAntihypertensive AgentsDesoxycorticosterone AcetateDisease Models, AnimalEndothelium, VascularHeart RateHypotensionMaleNG-Nitroarginine Methyl EsterPlant ExtractsRatsSapindaceaeVasodilationAntihypertensive AgentsDesoxycorticosterone AcetateNG-Nitroarginine Methyl EsterPlant Extracts

Identifiers

PMID33122667
PMCPMC7596469
OpenAlexW3097844393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.