Evidence map›Paper›PMID 33122315›Full record

ArticleBMJ open2020

Periconceptional surveillance for prevention of anaemia and birth defects in Southern India: protocol for a biomarker survey in women of reproductive age.

Julia L Finkelstein, Amy Fothergill, Christina B Johnson, Heather M Guetterman, Beena Bose, Shameem Jabbar, Mindy Zhang, Christine M Pfeiffer, Yan Ping Qi, Charles E Rose and 6 more

2 registry-linked trialsOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03853304 naunknown statusnot on this mapstarted 2023, after this paper: background citation

A Randomized Trial of Quadruple Fortified Salt for Anemia and Birth Defects Prevention in Southern India

TypeinterventionalSponsorCornell UniversityRan2023 to 2024Enrolled1,000ConditionsAnemia, Folate Deficiency, Vitamin B 12 DeficiencyArms+ Folic acid, + Vitamin B12, DFS
NCT04048330 unknown statusnot on this map

Periconceptional Surveillance for Prevention of Anemia and Birth Defects in India

TypeobservationalSponsorCornell UniversityRan2018 to 2024Enrolled2,000ConditionsAnemia, Folate Deficiency, Vitamin B12 Deficiency
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Review
  3. Vitamin BClinical nutrition ESPEN · 2025
    Observational
  4. Article
  5. Observational
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Julia L FinkelsteinDivision of Nutritional Sciences, Cornell University, Ithaca, New York, USA jfinkelstein@cornell.edu.ORCID 0000-0001-9512-5559
Amy FothergillDivision of Nutritional Sciences, Cornell University, Ithaca, New York, USA.
Christina B JohnsonArogyavaram Medical Centre, Madanapalle, Andhra Pradesh, India.
Heather M GuettermanDivision of Nutritional Sciences, Cornell University, Ithaca, New York, USA.
Beena BoseSt. John's Research Institute, Bangalore, Karnataka, India.
Shameem JabbarNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Mindy ZhangNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Christine M PfeifferNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Yan Ping QiNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Charles E RoseNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Jesse T KrisherDivision of Nutritional Sciences, Cornell University, Ithaca, New York, USA.
Caleb J RuthDivision of Nutritional Sciences, Cornell University, Ithaca, New York, USA.
Rajesh MehtaWorld Health Organization Regional Office for South-East Asia, New Delhi, Delhi, India.
Jennifer L WilliamsNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Wesley BonamArogyavaram Medical Centre, Madanapalle, Andhra Pradesh, India.
Krista S CriderNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Centers for Disease Control and Prevention · USCornell University · USSt.John's Medical College Hospital · INWorld Health Organization Regional Office for South-East Asia · IN

Funding

Coordinating Center for Research to Promote the Health of Children with Birth Defects and People with Developmental and Other DisabilitiesU19DD001218 · DD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI CAI, BO, CARLIN, ROBERTA · 2017 to 2021
$7.4M
TRAINING IN MATERNAL AND CHILD NUTRITIONT32HD087137 · NICHD · CORNELL UNIVERSITY · PI Laura Bellows, Julia L. Finkelstein · 2016 to 2026
$2.0M
ACL HHS U19DD001218NCBDD CDC HHS U19 DD001218NICHD NIH HHS T32 HD087137World Health Organization 001
6 · The paper itself

Abstract

introductionWomen of reproductive age (WRA) are a high-risk population for anaemia and micronutrient deficiencies. Evidence supports the role of periconceptional nutrition in the development of adverse pregnancy complications. However, in India, there are limited population-based data to guide evidence-based recommendations and priority setting. The objective of this study is to conduct a population-based biomarker survey of anaemia and vitamin B

methodsWRA (15-40 years) who are not pregnant or lactating and reside within 50 km ETHICS AND DISSEMINATION: This study has obtained clearance from the Health Ministry Screening Committee of the Indian Council of Medical Research. The study protocol was reviewed and approved by the Institutional Review Board at Cornell University and the Institutional Ethics Committees at Arogyavaram Medical Centre and St. John's Research Institute. Findings from this biomarker survey will establish the burden of anaemia and micronutrient deficiencies in WRA and directly inform a randomised trial for anaemia and birth defects prevention in Southern India. The results of this study will be disseminated at international research conferences and as published articles in peer-reviewed journals. TRIAL REGISTRATION NUMBERS: Clinical trials registration number NCT04048330, NCT03853304 and Clinical Trials Registry of India (CTRI) registration number REF/2019/03/024479.

Indexed as

AnemiaLactationBiomarkersFemaleHumansIndiaPregnancyVitamin B 12BiomarkersVitamin B 12anaemiaepidemiologygynaecologynutrition & dieteticsobstetricspublic health

Identifiers

PMID33122315
PMCPMC7597478
OpenAlexW3095614583

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.