Evidence map›Paper›PMID 33122214›Full record

ArticleAJNR. American journal of neuroradiology2020

Quantitative T1ρ MRI of the Head and Neck Discriminates Carcinoma and Benign Hyperplasia in the Nasopharynx.

Q Y H Ai, W Chen, T Y So, W K J Lam, B Jiang, D M C Poon, S Qamar, F K F Mo, T Blu, Q Chan and 4 more

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. T1rho imaging of head and neck cancer: its association with pathological and immunohistochemical biomarkers in nasopharyngeal carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 6 countries.

Q Y H AiFrom the Department of Imaging and Interventional Radiology (Q.Y.H.A., W.C., T.Y.S., B.J., S.Q., A.D.K.).ORCID 0000-0002-1155-4389
W ChenFrom the Department of Imaging and Interventional Radiology (Q.Y.H.A., W.C., T.Y.S., B.J., S.Q., A.D.K.) wtchen@cuhk.edu.hk.ORCID 0000-0001-7242-9285
T Y SoFrom the Department of Imaging and Interventional Radiology (Q.Y.H.A., W.C., T.Y.S., B.J., S.Q., A.D.K.).ORCID 0000-0001-8268-0721
W K J LamLi Ka Shing Institute of Health Sciences (W.K.J.L., D.M.C.P., B.B.Y.M., E.P.H., K.C.A.C.).ORCID 0000-0001-8922-5609
B JiangFrom the Department of Imaging and Interventional Radiology (Q.Y.H.A., W.C., T.Y.S., B.J., S.Q., A.D.K.).ORCID 0000-0002-2732-2152
D M C PoonLi Ka Shing Institute of Health Sciences (W.K.J.L., D.M.C.P., B.B.Y.M., E.P.H., K.C.A.C.).ORCID 0000-0002-6226-0743
S QamarFrom the Department of Imaging and Interventional Radiology (Q.Y.H.A., W.C., T.Y.S., B.J., S.Q., A.D.K.).ORCID 0000-0001-8763-3377
F K F MoDepartment of Clinical Oncology (D.M.C.P., F.K.F.M., B.B.Y.M., E.P.H.), State Key Laboratory in Oncology in South China, Sir Y.K. Pao Centre for Cancer, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, SAR.ORCID 0000-0002-0566-3212
T BluDepartment of Electrical Engineering (T.B.), The Chinese University of Hong Kong, Hong Kong, SAR.ORCID 0000-0001-5759-0011
Q ChanPhilips Healthcare (Q.C.), Hong Kong, SAR.ORCID 0000-0003-1270-995X
B B Y MaLi Ka Shing Institute of Health Sciences (W.K.J.L., D.M.C.P., B.B.Y.M., E.P.H., K.C.A.C.).ORCID 0000-0003-4802-1102
E P HuiLi Ka Shing Institute of Health Sciences (W.K.J.L., D.M.C.P., B.B.Y.M., E.P.H., K.C.A.C.).ORCID 0000-0002-8134-7019
K C A ChanLi Ka Shing Institute of Health Sciences (W.K.J.L., D.M.C.P., B.B.Y.M., E.P.H., K.C.A.C.).ORCID 0000-0003-1780-1691
A D KingFrom the Department of Imaging and Interventional Radiology (Q.Y.H.A., W.C., T.Y.S., B.J., S.Q., A.D.K.).ORCID 0000-0002-5280-8349
Chinese University of Hong Kong · HKSociety of Interventional Radiology · USDepartment of Health · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeT1ρ imaging is a new quantitative MR imaging pulse sequence with the potential to discriminate between malignant and benign tissue. In this study, we evaluated the capability of T1ρ imaging to characterize tissue by applying T1ρ imaging to malignant and benign tissue in the nasopharynx and to normal tissue in the head and neck. MATERIALS AND

methodsParticipants with undifferentiated nasopharyngeal carcinoma and benign hyperplasia of the nasopharynx prospectively underwent T1ρ imaging. T1ρ measurements obtained from the histogram analysis for nasopharyngeal carcinoma in 43 participants were compared with those for benign hyperplasia and for normal tissue (brain, muscle, and parotid glands) in 41 participants using the Mann-Whitney

resultsThere were significant differences in T1ρ measurements between nasopharyngeal carcinoma and benign hyperplasia and between nasopharyngeal carcinoma and normal tissue (all,

conclusionsQuantitative T1ρ imaging has the potential to discriminate malignant from benign and normal tissue in the head and neck.

Indexed as

AdultAgedAged, 80 and overFemaleHeadHumansHyperplasiaImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNasopharyngeal CarcinomaNasopharyngeal NeoplasmsNasopharynxNeckROC Curve

Identifiers

PMID33122214
PMCPMC7963257
OpenAlexW3097663184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.