Evidence map›Paper›PMID 33121898›Full record

ReviewTrends in microbiology2021

Molecular Logic of Prokaryotic Surface Layer Structures.

Tanmay A M Bharat, Andriko von Kügelgen, Vikram Alva

Open access · hybridAbstract readReview
In one paragraph

Review in Trends in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 84 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Cell surface differences within the genusJournal of bacteriology · 2025
    Review
  5. Cryo-EM structure and polar assembly of the PS2 S-layer ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. A self-assembling surface layer flattens the cytokinetic furrow to aid cell division in an archaeon.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Exploring proteinmBio · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Architecture of the Sap S-layer ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Article
  15. Article
  16. The Archaeal Cell Cycle.Annual review of cell and developmental biology · 2024
    Review
  17. Halofilins as emerging bactofilin families of archaeal cell shape plasticity orchestrators.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Tanmay A M BharatSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK; Central Oxford Structural Microscopy and Imaging Centre, University of Oxford, Oxford OX1 3RE, UK. Electronic address: tanmay.bharat@path.ox.ac.uk.
Andriko von KügelgenSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, UK; Central Oxford Structural Microscopy and Imaging Centre, University of Oxford, Oxford OX1 3RE, UK.
Vikram AlvaDepartment of Protein Evolution, Max Planck Institute for Developmental Biology, Max-Planck-Ring 5, Tübingen 72076, Germany. Electronic address: vikram.alva@tuebingen.mpg.de.
University of Oxford · GBMax Planck Institute for Developmental Biology · DE

Funding

Wellcome Trust 202231/Z/16/Z
6 · The paper itself

Abstract

Most prokaryotic cells are encased in a surface layer (S-layer) consisting of a paracrystalline array of repeating lattice-forming proteins. S-layer proteins populate a vast and diverse sequence space, performing disparate functions in prokaryotic cells, including cellular defense, cell-shape maintenance, and regulation of import and export of materials. This article highlights recent advances in the understanding of S-layer structure and assembly, made possible by rapidly evolving structural and cell biology methods. We underscore shared assembly principles revealed by recent work and discuss a common molecular framework that may be used to understand the structural organization of S-layer proteins across bacteria and archaea.

Indexed as

ArchaeaArchaeal ProteinsBacteriaBacterial ProteinsMembrane GlycoproteinsArchaeal ProteinsBacterial ProteinsMembrane GlycoproteinsS-layer proteinsbacterial cell envelopesbioinformaticsprotein evolutionstructural biologysurface layer

Identifiers

PMID33121898
PMCPMC8559796
OpenAlexW3096319119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.