Evidence map›Paper›PMID 33121614›Full record

ReviewClinics in laboratory medicine2020

Clinical Pathogen Genomics.

Andrew Cameron, Jessica L Bohrhunter, Samantha Taffner, Adel Malek, Nicole D Pecora

Abstract readReview
In one paragraph

Review in Clinics in laboratory medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Clinical metagenomics: ethical issues.Journal of medical microbiology · 2025
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrew CameronDepartment of Pathology and Laboratory Medicine, UR Medicine Central Laboratory, West Henrietta, NY 14586, USA.
Jessica L BohrhunterDepartment of Pathology and Laboratory Medicine, UR Medicine Central Laboratory, West Henrietta, NY 14586, USA.
Samantha TaffnerDepartment of Pathology and Laboratory Medicine, UR Medicine Central Laboratory, West Henrietta, NY 14586, USA.
Adel MalekFaculty of Laboratory Medicine, Memorial University, St John's, Newfoundland and Labrador, Canada.
Nicole D PecoraDepartment of Pathology and Laboratory Medicine, UR Medicine Central Laboratory, West Henrietta, NY 14586, USA. Electronic address: nicole_pecora@urmc.rochester.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent improvements in next-generation sequencing technologies have enabled clinical laboratories to increasingly pursue pathogen genomics for infectious disease diagnosis. Clinical laboratories can also benefit from whole-genome sequence characterization of cultured isolates, helping to resolve infection prevention questions pertaining to pathogen outbreaks and surveillance. Metagenomic sequencing from primary specimens can also provide laboratories with an unbiased universal test for situations where traditional methods fail to identify infectious etiologies despite, high clinical suspicion. Here, the most useful applications of whole-genome sequence and metagenomic sequencing are summarized, as are the main advantages, limitations, and considerations for building an in-house clinical genomics program.

Indexed as

GenomicsMicrobiological TechniquesMolecular Diagnostic TechniquesWhole Genome SequencingBacterial InfectionsHigh-Throughput Nucleotide SequencingHumansMetagenomicsMycosesClinical metagenomicsClinical pathogen genomicsNext-generation sequencingPathogen whole-genome sequencing

Identifiers

PMID33121614
PMCPMC7528835

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.