Evidence map›Paper›PMID 33121479›Full record

ArticleBMC medical informatics and decision making2020

Combining structured and unstructured data for predictive models: a deep learning approach.

Dongdong Zhang, Changchang Yin, Jucheng Zeng, Xiaohui Yuan, Ping Zhang

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dongdong ZhangDepartment of Biomedical Informatics, The Ohio State University, 1800 Cannon Drive, Columbus, OH, 43210, USA.
Changchang YinDepartment of Computer Science and Engineering, The Ohio State University, 2015 Neil Ave, Columbus, OH, 43210, USA.
Jucheng ZengDepartment of Biomedical Informatics, The Ohio State University, 1800 Cannon Drive, Columbus, OH, 43210, USA.
Xiaohui YuanSchool of Computer Science and Technology, Wuhan University of Technology, Wuhan, 430070, Hubei, China.
Ping ZhangDepartment of Biomedical Informatics, The Ohio State University, 1800 Cannon Drive, Columbus, OH, 43210, USA. mail.pingzhang@gmail.com.ORCID 0000-0002-4601-0779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe broad adoption of electronic health records (EHRs) provides great opportunities to conduct health care research and solve various clinical problems in medicine. With recent advances and success, methods based on machine learning and deep learning have become increasingly popular in medical informatics. However, while many research studies utilize temporal structured data on predictive modeling, they typically neglect potentially valuable information in unstructured clinical notes. Integrating heterogeneous data types across EHRs through deep learning techniques may help improve the performance of prediction models.

methodsIn this research, we proposed 2 general-purpose multi-modal neural network architectures to enhance patient representation learning by combining sequential unstructured notes with structured data. The proposed fusion models leverage document embeddings for the representation of long clinical note documents and either convolutional neural network or long short-term memory networks to model the sequential clinical notes and temporal signals, and one-hot encoding for static information representation. The concatenated representation is the final patient representation which is used to make predictions.

resultsWe evaluate the performance of proposed models on 3 risk prediction tasks (i.e. in-hospital mortality, 30-day hospital readmission, and long length of stay prediction) using derived data from the publicly available Medical Information Mart for Intensive Care III dataset. Our results show that by combining unstructured clinical notes with structured data, the proposed models outperform other models that utilize either unstructured notes or structured data only.

conclusionsThe proposed fusion models learn better patient representation by combining structured and unstructured data. Integrating heterogeneous data types across EHRs helps improve the performance of prediction models and reduce errors.

Indexed as

Deep LearningMachine LearningNeural Networks, ComputerElectronic Health RecordsHumansPatient ReadmissionData fusionDeep learningElectronic health recordsTime series forecasting

Identifiers

PMID33121479
PMCPMC7596962

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.