ArticleBMC endocrine disorders2020
Stereological assessment of the effects of vitamin D deficiency on the rat testis.
Article in BMC endocrine disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Chlorella vulgaris and Lactobacillus casei Improve Liver Dysfunction via UPR and Autophagy in High-Fat Diet-Induced NAFLD in Mice.Probiotics and antimicrobial proteins · 2026Article
- Combined vitamin D and coconut oil are promising protective approaches against aluminum-induced testicular damage in rats.Toxicology reports · 2025Article
- The effects of modest intake of soy milk enriched with Lactobacillus casei and omega-3 on the testis parameters in diabetic rats: a stereological study.International urology and nephrology · 2025Article
- Therapeutic Potential ofInternational journal of endocrinology · 2025Article
- "Protective effects of artichoke extract and Bifidobacterium longum on male infertility in diabetic rats".Biochemistry and biophysics reports · 2024Article
- Histopathological evaluation of infertility: Lessons from laboratory rodents.Histology and histopathology · 2024Review
- The role of anti-aging approaches in managing hypogonadism in sedentary older males.Frontiers in aging · 2024Review
- The role of the transsulfuration pathway in spermatogenesis of vitamin D deficient mice.Scientific reports · 2023Article
- The Association between Vitamin D and the Components of Male Fertility: A Systematic Review.Biomedicines · 2022Review
- The protective effect of L-carnitine on testosterone synthesis pathway, and spermatogenesis in monosodium glutamate-induced rats.BMC complementary medicine and therapies · 2022Article
- Ellagic acid effects on testis, sex hormones, oxidative stress, and apoptosis in the relative sterility rat model following busulfan administration.BMC complementary medicine and therapies · 2022Article
- Accurate Quantitative Histomorphometric-Mathematical Image Analysis Methodology of Rodent Testicular Tissue and Its Possible Future Research Perspectives in Andrology and Reproductive Medicine.Life (Basel, Switzerland) · 2022Article
- The effects of L-carnitine on renal function and gene expression of caspase-9 and Bcl-2 in monosodium glutamate-induced rats.BMC nephrology · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccumulating evidence suggests that low vitamin D status may affect male gonadal structure. This study was undertaken to reveal whether vitamin D-deficient rats have demonstrable changes in the quantitative histomorphometric properties of the testis.
methodsIn the present investigation, adult male Sprague-Dawley rats were divided into four groups and received: group 1) conventional diet; group 2) vitamin D-deficient diet; group 3) vitamin D-deficient diet and paricalcitol and group 4) conventional diet plus paricalcitol. After 3 months, serum levels of vitamin D metabolites, Ca, P, LH, FSH, testosterone, and epididymal sperm quality were evaluated. Moreover, the morphometric characteristics of testis were assessed via stereological methods.
resultsRats fed a vitamin D-deficient diet (groups 2 and 3) were normocalcemic and had 25-hydroxyvitamin D
conclusionsThe depletion of vitamin D stores and induction of moderate grades of vitamin D deficiency by dietary measures led to remarkable impairment of spermatogenesis and microscopic architecture of rat testis. These findings can be attributed, at least in part, to decreased androgen production.
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