Evidence map›Paper›PMID 33121330›Full record

ArticleHuman vaccines & immunotherapeutics2021

HPV vaccine acceptability and willingness-related factors among Chinese adolescents: a nation-wide study.

Xi Zhang, Zengzhen Wang, Zefang Ren, Zhifang Li, Wei Ma, Xiaohong Gao, Rong Zhang, Youlin Qiao, Jing Li

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06227689 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Evaluation of Vaccine Chatbot on HPV Vaccine Awareness and Vaccination for Middle School Girls in China: a Randomized Controlled Trial and Implementation Science Study

TypeinterventionalSponsorFudan UniversityRan2024 to 2024Enrolled1,800ConditionsHPV VaccineArmsVaccine chatbot that offering HPV vaccine-related information
NCT07200570 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluation of a Vaccine Chatbot on HPV Vaccine Confidence and Hesitancy: a Randomized Controlled Trial and Implementation Science Study

TypeinterventionalSponsorFudan UniversityRan2026 to 2026Enrolled1,800ConditionsHPV VaccineArmsLLM-Powered HPV Vaccine Chatbot
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 2 countries.

Xi ZhangKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Beijing Office for Cancer Prevention and Control, Peking University Cancer Hospital & Institute, Beijing, China.ORCID 0000-0001-7402-6981
Zengzhen WangDepartment of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Zefang RenDepartment of Epidemiology and Biostatistics, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Zhifang LiDepartment of Public Health and Preventive Medicine, Changzhi Medical College, Changzhi, China.ORCID 0000-0002-7934-904X
Wei MaDepartment of Epidemiology, School of Public Health, Shandong University, Jinan, China.
Xiaohong GaoDepartment of Epidemiology, School of Public Health, Dalian Medical University, Dalian, China.
Rong ZhangPostdoctoral Research Station, Xinjiang Uygur Autonomous Region Center for Disease Control and Prevention, Urumqi, China.
Youlin QiaoCancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College School of population medicine & public health, Beijing, China.
Jing LiDepartment of Occupational and Environmental Health, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Changzhi Medical College · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNDalian Medical University · CNHuazhong University of Science and Technology · CNPeking University · CNShandong University · CNSun Yat-sen University · CNWest China Medical Center of Sichuan University · CNXinjiang Uygur Autonomous Region Disease Prevention and Control Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdolescents are the primary target population for human papillomavirus (HPV) vaccination. The objective of this study is to explore the acceptability of HPV vaccines and evaluate factors related to willingness to be vaccinated among Chinese adolescents.

methodsA nation-wide survey was conducted across 14 schools in mainland China. The questionnaire consisted of questions relating to socio-demographic characteristics, knowledge of adolescent sexual health, cervical cancer, HPV and HPV-related disease, and students' willingness to be vaccinated.

resultsA total of 4,062 students participated in this study. Among them, only 17.1% of students reported having heard of HPV vaccines; however, 67.3% were willing to receive the HPV vaccine. Multivariable regression analysis showed that students who were from rural areas, have received sexual health education, have heard of cervical cancer or HPV vaccine, have a positive attitude toward vaccination, reported they were at the risk of developing cervical cancer, and those who value their parents' and teachers' opinions were more willing to receive HPV vaccination.

conclusionsAwareness about the HPV vaccine is low among Chinese adolescents. The factors that most related to willingness to vaccinate among Chinese adolescents were school location, education about vaccination, HPV, and HPV vaccines. Integrating health education on HPV vaccination into existing school-based sexual health curricula may be an effective way to increase HPV vaccination coverage in mainland China.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsAdolescentChinaFemaleHealth Knowledge, Attitudes, PracticeHumansPatient Acceptance of Health CareSurveys and QuestionnairesVaccinationPapillomavirus Vaccinesadolescentsassociated factorsChinaHPV vaccinewillingness to receive

Identifiers

PMID33121330
PMCPMC8018488
OpenAlexW3096418104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.