Evidence map›Paper›PMID 33121320›Full record

ArticleCancer biology & therapy2020

Ototoxicity in patients with invasive ductal breast cancer who were treated with docetaxel: report of two cases.

Liang Xuan, Bing Sun, Xiangying Meng, Chao Liu, Yang Cong, Shikai Wu

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Cancer biology & therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Ototoxicity beyond platinum-based derivatives.Cancer chemotherapy and pharmacology · 2026
    Article
  2. Review
  3. Observational
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Liang XuanDepartment of Radiation Oncology, The Fifth Medical Center, Chinese PLA General Hospital , Beijing, China.
Bing SunDepartment of Radiation Oncology, The Fifth Medical Center, Chinese PLA General Hospital , Beijing, China.
Xiangying MengDepartment of Radiation Oncology, The Fifth Medical Center, Chinese PLA General Hospital , Beijing, China.
Chao LiuDepartment of Radiation Oncology, The Fifth Medical Center, Chinese PLA General Hospital , Beijing, China.
Yang CongDepartment of Radiation Oncology, The Fifth Medical Center, Chinese PLA General Hospital , Beijing, China.
Shikai WuDepartment of Medical Oncology, Peking University First Hospital , Beijing, China.
Chinese PLA General Hospital · CNPeking University First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Docetaxel is an important anti-microtubule agent used to treat a variety of solid tumors, including breast cancer; notably, docetaxel-containing regimens improve outcomes for patients in metastatic, adjuvant, and neoadjuvant settings. However, the effectiveness of docetaxel in clinical practice can be compromised by suboptimal management of side effects. Here, we report two cases of docetaxel-based chemotherapy regimens in patients who exhibited invasive ductal breast cancer and underwent two different clinical treatment approaches. A 58-year-old postmenopausal female received salvage treatment with 8 cycles of docetaxel (67 mg/m

Indexed as

Antineoplastic AgentsBreast NeoplasmsDocetaxelFemaleHumansMiddle AgedOtotoxicityAntineoplastic AgentsDocetaxelBreast cancerdocetaxelototoxicitysensorineural hearing losstaxanes

Identifiers

PMID33121320
PMCPMC7678920
OpenAlexW3095184244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.