Evidence map›Paper›PMID 33121314›Full record

ArticleCell cycle (Georgetown, Tex.)2020

Silencing miR-125b-5p attenuates inflammatory response and apoptosis inhibition in mycobacterium tuberculosis-infected human macrophages by targeting DNA damage-regulated autophagy modulator 2 (DRAM2).

Guangming Liu, Qiufeng Wan, Jingwen Li, Xinying Hu, Xingli Gu, Sicheng Xu

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Participation of miRNA-23a-3p in Pulmonary Tuberculosis Through Macrophages via the JAK-STAT Pathway.International journal of chronic obstructive pulmonary disease · 2026
    Article
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  7. Article
  8. Functional Analysis of Genes inIndian journal of microbiology · 2024
    Review
  9. Article
  10. Article
  11. LncRNA NR_003508 SuppressesInternational journal of molecular sciences · 2023
    Article
  12. Article
  13. Frontiers in cellular and infection microbiology · 2023
    Review
  14. Article
  15. Integration of human stem cell-derivedFrontiers in cell and developmental biology · 2023
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Guangming LiuDepartment of Respiratory Intensive Care Unit, The First Affiliated Hospital of Xinjiang Medical University , Xinjiang, China.
Qiufeng WanDepartment of Respiratory Intensive Care Unit, The First Affiliated Hospital of Xinjiang Medical University , Xinjiang, China.
Jingwen LiDepartment of Respiratory Intensive Care Unit, The First Affiliated Hospital of Xinjiang Medical University , Xinjiang, China.
Xinying HuDepartment of Respiratory Intensive Care Unit, The First Affiliated Hospital of Xinjiang Medical University , Xinjiang, China.
Xingli GuDepartment of Respiratory Intensive Care Unit, The First Affiliated Hospital of Xinjiang Medical University , Xinjiang, China.
Sicheng XuDepartment of Respiratory Intensive Care Unit, The First Affiliated Hospital of Xinjiang Medical University , Xinjiang, China.
First Affiliated Hospital of Xinjiang Medical University · CNXinjiang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis is one of the most important infectious diseases worldwide and macrophage apoptosis is the major host defense mechanism against TB. We attempted to characterize the role of miRNA (miR)-125b-5p on mycobacterium tuberculosis (Mtb) infection and macrophages behaviors

Indexed as

Gene SilencingAdultApoptosisCase-Control StudiesDown-RegulationFemaleHumansInflammationMacrophagesMaleMembrane ProteinsMicroRNAsMiddle AgedMonocytesMycobacterium tuberculosisSignal TransductionDRAM2 protein, humanMembrane ProteinsMicroRNAsMIRN125 microRNA, humanapoptosisDRAM2macrophageMir-125b-5pmycobacterium tuberculosis

Identifiers

PMID33121314
PMCPMC7714508
OpenAlexW3096329738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.