Evidence map›Paper›PMID 33121257›Full record

ArticleAmerican journal of rhinology & allergy2021

Short-Term Morbidity and Predictors of Adverse Events Following Esthesioneuroblastoma Surgery.

Khodayar Goshtasbi, Jack L Birkenbeuel, Mehdi Abouzari, Brandon M Lehrich, Tyler M Yasaka, Arash Abiri, Ethan G Muhonen, Frank P K Hsu, Edward C Kuan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of rhinology & allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Khodayar GoshtasbiDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California.ORCID https://orcid.org/0000-0002-0045-2547
Jack L BirkenbeuelDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California.ORCID https://orcid.org/0000-0002-2133-7708
Mehdi AbouzariDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California.ORCID https://orcid.org/0000-0002-3585-698X
Brandon M LehrichDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California.
Tyler M YasakaDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California.ORCID https://orcid.org/0000-0002-8482-0369
Arash AbiriDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California.ORCID https://orcid.org/0000-0003-2656-1060
Ethan G MuhonenDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California.ORCID https://orcid.org/0000-0002-6556-4507
Frank P K HsuDepartment of Neurological Surgery, University of California, Irvine, California.
Edward C KuanDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California.ORCID https://orcid.org/0000-0003-3475-0718
University of California, Irvine · US

Funding

NRSA Training CoreTL1TR001415 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI CAIOZZO, VINCENT JAMES, HEAD, ELIZABETH · 2015 to 2023
$4.2M
NCATS NIH HHS TL1 TR001415
6 · The paper itself

Abstract

introductionThe short-term adverse events and predictors of morbidity in surgical resection of esthesioneuroblastoma (ENB) are largely unknown, and investigating these variables can help direct planning for at-risk patients.

methodsThe 2005-2017 National Surgical Quality Improvement Program database was queried to identify patients with a diagnosis of ENB undergoing skull base surgery for tumor resection. Information regarding demographics, patient morbidity score, pre-operative and intra-operative data, and post-operative outcomes were extracted. Cox proportional hazard analysis was utilized to assess complication and readmission/reoperation rates.

resultsA total of 95 patients undergoing skull base surgery for resection of ENB were included. Mean age, BMI, operation time, and post-operative length of stay (LOS) of the cohort were 53.6 ± 16.2 years, 29.1 ± 6.5, 392.0 ± 204.6 minutes, and 5.8 ± 4.6 days, respectively. In total, 31 patients (32.6%) experienced at least one 30-day adverse event, which included blood transfusion intra-operatively or within 72 hours from the operation (22.1%), readmission (10.7%), intubation >48 hours (7.4%), reintubation (4.2%), organ or space infection (4.2%), reoperation (4.0%), superficial or deep surgical site infection (2.1%), sepsis (2.1%), pulmonary embolism (1.1%), and myocardial infarction (1.1%). Patients who experienced at least one adverse event had significantly higher operation time (486.8 ± 230.4 vs. 347.5 ± 176.2 minutes,

conclusionLonger operation time and lower pre-operative hematocrit and albumin levels may all increase complication rates in ENB resection. Patients with high ASA score or more advanced age may have different short-term outcomes.

Indexed as

Esthesioneuroblastoma, OlfactoryNose NeoplasmsHumansLength of StayMorbidityNasal CavityPostoperative ComplicationsReoperationRetrospective StudiesRisk Factorsesthesioneuroblastomamorbidity and mortalityNational Surgical Quality Improvement Programolfactory neuroblastoma

Identifiers

PMID33121257
PMCPMC8822193
OpenAlexW3097571109

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.