Evidence map›Paper›PMID 33121218›Full record

ArticleESC heart failure2020

Early rehabilitation after stroke: relationship between the heart rate variability and functional outcome.

Nadja Scherbakov, Anush Barkhudaryan, Nicole Ebner, Stephan von Haehling, Stefan D Anker, Michael Joebges, Wolfram Doehner

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Autonomic dysfunction after stroke: an overview of recent clinical evidence and perspectives on therapeutic management.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Dysautonomia and activity in the early stroke recovery period.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Review
  12. Observational
  13. Nonpharmacological Treatments for Hospitalized Patients with Stroke: A Nuanced Approach to Prescribing Early Activity.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  14. Article
  15. WHOLE-BODY CRYOSTIMULATION: A REHABILITATION BOOSTER.Journal of rehabilitation medicine. Clinical communications · 2022
    Article
  16. Cardiovascular autonomic dysfunction after stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Nadja ScherbakovBerlin-Brandenburg Center for Regenerative Therapies (BCRT), Center for Stroke Research Berlin (CSB), Charité Universitätsmedizin Berlin, Berlin, Germany.
Anush BarkhudaryanDepartment of Cardiology, Clinic of General and Invasive Cardiology, University Hospital No. 1, Yerevan State Medical University, Yerevan, Armenia.
Nicole EbnerDepartment of Cardiology and Pneumology, University Medical Center Göttingen (UMG), Göttingen, Germany.
Stephan von HaehlingDepartment of Cardiology and Pneumology, University Medical Center Göttingen (UMG), Göttingen, Germany.
Stefan D AnkerBerlin-Brandenburg Center for Regenerative Therapies (BCRT), Center for Stroke Research Berlin (CSB), Charité Universitätsmedizin Berlin, Berlin, Germany.
Michael JoebgesClinic for Neurology and Neurological Rehabilitation, Schmieder Clinic (Stiftung Co.) KG, Konstanz, Germany.
Wolfram DoehnerBerlin-Brandenburg Center for Regenerative Therapies (BCRT), Center for Stroke Research Berlin (CSB), Charité Universitätsmedizin Berlin, Berlin, Germany.
German Centre for Cardiovascular Research · DEBerlin-Brandenburger Centrum für Regenerative Therapien · DECharité - Universitätsmedizin Berlin · DEKliniken Schmieder · DEUniversitätsmedizin Göttingen · DEYerevan State Medical University · AM

Funding

German Academic Exchange Service (DAAD)German Federal Ministry of Education and Research (BMBF) EO 0801
6 · The paper itself

Abstract

aimsImpaired autonomic nervous system regulation is frequently observed in patients with stroke. The aim of this prospective study was to evaluate the impact of cardiac autonomic tone on functional outcome after the early post-stroke rehabilitation. METHODS AND

resultsOne hundred and three consecutive patients (67 ± 11 years, body mass index (BMI) 27.1 ± 5.4 kg/m

conclusionsThe presence of autonomic cardiovascular dysregulation in patients with subacute stroke was associated with adverse functional outcome after the early post-stroke rehabilitation.

Indexed as

StrokeAutonomic Nervous SystemFemaleHeartHeart RateHumansMaleProspective StudiesFunctional outcomeHeart rate variabilityRehabilitationStroke

Identifiers

PMID33121218
PMCPMC7524118
OpenAlexW3046348826

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.