Evidence map›Paper›PMID 33121195›Full record

ArticleJournal of clinical medicine2020

Coagulation Changes during Central Hypovolemia across Seasons.

Nandu Goswami, Alexander Andreas Taucher, Bianca Brix, Andreas Roessler, Martin Koestenberger, Gilbert Reibnegger, Gerhard Cvirn

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nandu GoswamiPhysiology Division, Otto Loewi Research Center, Medical University of Graz, 8036 Graz, Austria.
Alexander Andreas TaucherPhysiology Division, Otto Loewi Research Center, Medical University of Graz, 8036 Graz, Austria.
Bianca BrixPhysiology Division, Otto Loewi Research Center, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-7308-5450
Andreas RoesslerPhysiology Division, Otto Loewi Research Center, Medical University of Graz, 8036 Graz, Austria.
Martin KoestenbergerDepartment of Pediatric Cardiology, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0003-1766-7859
Gilbert ReibneggerPhysiological Chemistry Division, Otto Loewi Research Center, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0001-7202-2426
Gerhard CvirnPhysiological Chemistry Division, Otto Loewi Research Center, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0002-1410-1844

Funding

Otto Loewi Center of Research in Vascular Biology, Immunity and Inflammation of the Medical University of Graz internal research grant
6 · The paper itself

Abstract

Lower body negative pressure (LBNP) application simulates hemorrhage. We investigated how seasons affect coagulation values at rest and during LBNP. Healthy participants were tested in cold (November-April) and warm (May-October) months. Following a 30-min supine period, LBNP was started at -10 mmHg and increased by -10 mmHg every five minutes until a maximum of -40 mmHg. Recovery was for 10 min. Blood was collected at baseline, end of LBNP, and end of recovery. Hemostatic profiling included standard coagulation tests, calibrated automated thrombogram, thrombelastometry, impedance aggregometry, and thrombin formation markers. Seven men (25.0 ± 3.6 years, 79.7 ± 7.8 kg weight, 182.4 ± 3.3 cm height, and 23.8 ± 2.3 kg/m

Indexed as

coagulationLBNPseasonsthrombelastometrythrombin generationtrhombogram

Identifiers

PMID33121195
PMCPMC7692650

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.