Evidence map›Paper›PMID 33121150›Full record

ArticleDiagnostics (Basel, Switzerland)2020

The Value of Strain Elastography in Predicting Autoimmune Thyroiditis.

Cristina Mihaela Cepeha, Corina Paul, Andreea Borlea, Florin Borcan, Renata Fofiu, Cristina Adriana Dehelean, Dana Stoian

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  4. Observational
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cristina Mihaela CepehaPhD School Department, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Corina PaulDepartment of Pediatrics, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Andreea BorleaPhD School Department, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0001-6046-9191
Florin BorcanFaculty of Pharmacy, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0003-3406-0303
Renata FofiuPhD School Department, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Cristina Adriana DeheleanFaculty of Pharmacy, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Dana StoianDepartment of Internal Medicine II, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0003-3826-4362
Victor Babeș University of Medicine and Pharmacy Timișoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic autoimmune thyroiditis (CAT) defines a diffuse intrathyroidal lymphocytic infiltration associating a destructive process of the thyroid follicles, most commonly in evolution developing hypothyroidism. Typical ultrasound changes may suggest the presence of the disease. This study aims to evaluate the performance of strain elastography in detecting autoimmune thyroiditis as an additional tool to the conventional ultrasound examination. A total of 250 patients were enrolled in the study; 180 had biochemical confirmation of CAT, the other 70 healthy subjects represented the control group. All patients were examined clinically and by means of conventional thyroid ultrasound (US) and real-time elastography using a Hitachi Preirus machine (5-15 MHz linear probe). Five valid measurements for the parenchyma/muscle strain ratios (SR) were taken for each subject, considering the mean value for analysis. A mean SR value above 1.64 was found to predict the presence of CAT with sensitivity (Sen) 69%, specificity p92%, positive predictive value (PPV) 95.4%, negative predictive value (NPV) 54% and area under receiver operating characteristic (AUROC) 0.87. Moreover, when comparing the mean values for SR, significantly higher values were found in CAT patients compared with the controls (2.81 ± 2.11 vs. 1.03 ± 0.51;

Indexed as

autoimmune diseaseelastographyHashimotostrain ratiothyroid stiffness

Identifiers

PMID33121150
PMCPMC7692451
OpenAlexW3096229989

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.