Evidence map›Paper›PMID 33121148›Full record

ReviewInternational journal of molecular sciences2020

Contact-Dependent Growth Inhibition in Bacteria: Do Not Get Too Close!

Larisa N Ikryannikova, Leonid K Kurbatov, Neonila V Gorokhovets, Andrey A Zamyatnin

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Determination of the genome-scale metabolic network ofFrontiers in bioengineering and biotechnology · 2025
    Article
  6. The gut commensalFrontiers in microbiology · 2025
    Article
  7. Uncoupling growth and division inISME communications · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Genomic Analysis ofInternational journal of molecular sciences · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Pathogenicity assessment of Shiga toxin-producingFrontiers in microbiology · 2023
    Article
  17. Article
  18. Article
  19. Potential ProbioticMicroorganisms · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Larisa N IkryannikovaInstitute of Molecular Medicine, Sechenov First Moscow State Medical University, Trubetskaya 8/2, 119991 Moscow, Russia.
Leonid K KurbatovOrekhovich Research Institute of Biomedical Chemistry, Pogodinskaya 10/8, 119991 Moscow, Russia.
Neonila V GorokhovetsInstitute of Molecular Medicine, Sechenov First Moscow State Medical University, Trubetskaya 8/2, 119991 Moscow, Russia.
Andrey A ZamyatninInstitute of Molecular Medicine, Sechenov First Moscow State Medical University, Trubetskaya 8/2, 119991 Moscow, Russia.ORCID 0000-0002-3046-4565
Sechenov University · RUInstitute of Biomedical Chemistry · RU

Funding

Ministry of Science and Higher Education of the Russian Federation "Project 5-100" Russian Academic Excellence Project
6 · The paper itself

Abstract

Over millions of years of evolution, bacteria have developed complex strategies for intra-and interspecies interactions and competition for ecological niches and resources. Contact-dependent growth inhibition systems (CDI) are designed to realize a direct physical contact of one bacterial cell with other cells in proximity via receptor-mediated toxin delivery. These systems are found in many microorganisms including clinically important human pathogens. The main purpose of these systems is to provide competitive advantages for the growth of the population. In addition, non-competitive roles for CDI toxin delivery systems including interbacterial signal transduction and mediators of bacterial collaboration have been suggested. In this review, our goal was to systematize the recent findings on the structure, mechanisms, and purpose of CDI systems in bacterial populations and discuss the potential biological and evolutionary impact of CDI-mediated interbacterial competition and/or cooperation.

Indexed as

BacteriaBacterial ProteinsBiofilmsContact InhibitionMicrobial InteractionsBacterial Proteinsantibacterial toxinsbacterial communitiescontact-dependent growth inhibition (CDI)intra-and interspecies competition

Identifiers

PMID33121148
PMCPMC7662968
OpenAlexW3095717246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.