Evidence map›Paper›PMID 33121063›Full record

ArticleMedicina (Kaunas, Lithuania)2020

Tunneled Peritoneal Catheter for Refractory Ascites in Cirrhosis: A Randomized Case-Series.

Nina Kimer, Agnete Nordheim Riedel, Lise Hobolth, Christian Mortensen, Lone Galmstrup Madsen, Mette Lehmann Andersen, Frank Vinholdt Schiødt, Søren Møller, Lise Lotte Gluud

Abstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nina KimerGastro Unit, Medical Division, Hvidovre University Hospital, 2650 Hvidovre, Denmark.ORCID 0000-0002-4807-1575
Agnete Nordheim RiedelGastro Unit, Medical Division, Hvidovre University Hospital, 2650 Hvidovre, Denmark.ORCID 0000-0002-3532-1272
Lise HobolthGastro Unit, Medical Division, Hvidovre University Hospital, 2650 Hvidovre, Denmark.
Christian MortensenGastro Unit, Medical Division, Hvidovre University Hospital, 2650 Hvidovre, Denmark.
Lone Galmstrup MadsenDepartment of Clinical Medicine, University Hospital Køge, 4600 Køge, Denmark.
Mette Lehmann AndersenDepartment of Gastroenterology, University Hospital Herlev, 2630 Herlev, Denmark.
Frank Vinholdt SchiødtAbdominal Center K, University Hospital Bispebjerg, 2400 Copenhagen NV, Denmark.
Søren MøllerCenter of Functional and Diagnostic Imaging and Research, Department of Clinical and Nuclear Medicine, Amager-Hvidovre University Hospital, 2650 Hvidovre, Denmark.
Lise Lotte GluudGastro Unit, Medical Division, Hvidovre University Hospital, 2650 Hvidovre, Denmark.

Funding

BD Carefusion PleurX-50-7510Det Sundhedsvidenskabelige Fakultet, Københavns Universitet INT-2015
6 · The paper itself

Abstract

BACKGROUND AND

objectivesRefractory ascites markedly worsens prognosis in cirrhosis. Large volume paracentesis (LVP) is standard treatment, but complications are common. In a randomized controlled case-series, we assessed a permanent tunneled peritoneal catheter versus LVP in patients with cirrhosis and ascites. MATERIALS AND

methodsRandom allocation was computer-generated, and concealment used opaque envelopes. Patients were included from January 2017 to December 2018. Inclusion criteria were cirrhosis and recurrent ascites and expected survival of more than 3 months.

resultsThirteen patients were enrolled (PleurX =6 versus LVP = 7). Seven were female, ranging in age from 51 to 80 years. No procedure-related complications occurred. Two patients died due to variceal bleeding (PleurX-group) and sepsis (LVP-group). One patient was withdrawn due to hyponatremia (PleurX-group). Two patients were withdrawn due to bacterial peritonitis and infection of unknown origin (control-group). In the PleurX-group, all patients colonized the catheter, two developed bacterial peritonitis. The most common bacterial colonization was

conclusionsIn selected patients, the PleurX catheter mobilizes ascites and may be an alternative to LVP. The risk of infection should be considered in each case. The impact of colonization and risk of infections needs further investigation. The present trial does not allow for statistical conclusions.

Indexed as

AscitesEsophageal and Gastric VaricesAgedAged, 80 and overFemaleGastrointestinal HemorrhageHumansLiver CirrhosisMaleMiddle AgedParacentesisliver cirrhosisperitoneal catheterPleurXrefractory ascitesspontaneous bacterial peritonitis

Identifiers

PMID33121063
PMCPMC7692861

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.