Evidence map›Paper›PMID 33121016›Full record

ArticleMolecules (Basel, Switzerland)2020

Identification of Anti-Inflammatory Compounds from Hawaiian Noni (

Dahae Lee, Jae Sik Yu, Peng Huang, Mallique Qader, Arulmani Manavalan, Xiaohua Wu, Jin-Chul Kim, Changhyun Pang, Shugeng Cao, Ki Sung Kang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 43 citations in OpenAlex.

  1. FermentedNutrients · 2022
    Trial
  2. International journal of molecular sciences · 2026
    Article
  3. Active Components ofAntioxidants (Basel, Switzerland) · 2026
    Article
  4. Antioxidants (Basel, Switzerland) · 2025
    Review
  5. Inhibitory Effects of Compounds Isolated fromJournal of microbiology and biotechnology · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Anti-Inflammatory Effects ofMedicines (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Dahae LeeCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Jae Sik YuSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Peng HuangDaniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo, HI 96720, USA.ORCID 0000-0003-4839-8129
Mallique QaderDaniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo, HI 96720, USA.
Arulmani ManavalanDaniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo, HI 96720, USA.
Xiaohua WuDaniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo, HI 96720, USA.
Jin-Chul KimNatural Product Informatics Research Center, KIST Gangneung Institute of Natural Products, Gangneung 25451, Korea.
Changhyun PangSchool of Chemical Engineering, Sungkyunkwan University, Suwon 16419, Korea.
Shugeng CaoDaniel K. Inouye College of Pharmacy, University of Hawaii at Hilo, Hilo, HI 96720, USA.ORCID 0000-0001-6684-8221
Ki Sung KangCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Ki Hyun KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.ORCID 0000-0002-5285-9138
University of Hawaii at Hilo · USSungkyunkwan University · KRGachon University · KR

Funding

National Research Foundation of Korea 2018R1A2B2006879 and 2019R1A5A2027340, NRF-2012M3A9C4048775
6 · The paper itself

Abstract

Noni (

Indexed as

AnimalsAnti-Inflammatory AgentsCell SurvivalCyclooxygenase 2Fruit and Vegetable JuicesGene Expression RegulationI-kappa B KinaseI-kappa B ProteinsMacrophagesMiceMorindaNitric OxideNitric Oxide Synthase Type IIRAW 264.7 CellsTranscription Factor RelAAnti-Inflammatory AgentsCyclooxygenase 2I-kappa B KinaseI-kappa B ProteinsNitric OxideNitric Oxide Synthase Type IITranscription Factor RelAanti-inflammationMorinda citrifolianoniNO productionRAW 264.7 cells

Identifiers

PMID33121016
PMCPMC7662328
OpenAlexW3096953016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.