Evidence map›Paper›PMID 33120985›Full record

ArticleMolecules (Basel, Switzerland)2020

Novel Pathway of Adenosine Generation in the Lungs from NAD

Richard Graeff, Alonso Guedes, Ruth Quintana, Erin Wendt-Hornickle, Caroline Baldo, Timothy Walseth, Scott O'Grady, Mathur Kannan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. The Role of NADPharmaceuticals (Basel, Switzerland) · 2024
    Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Richard GraeffDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Alonso GuedesDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0002-7980-9018
Ruth QuintanaDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Erin Wendt-HornickleDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Caroline BaldoDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.
Timothy WalsethDepartment of Pharmacology, University of Minnesota Medical School, University of Minnesota, St. Paul, MN 55455, USA.
Scott O'GradyDepartment of Animal Science, College of Food, Agricultural and Natural Resource Sciences, University of Minnesota, St. Paul, MN 55108, USA.
Mathur KannanDepartment of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.ORCID 0000-0003-3624-4050
University of Minnesota · USUniversity of Minnesota Medical Center · US

Funding

NIH HHS 1R21AI119395-01A1NIH HHS R01-AI128729U.S. Department of Agriculture AES0016097
6 · The paper itself

Abstract

Adenosine and uric acid (UA) play a pivotal role in lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). In the present experiments, we measured adenosine synthesis from nicotinamide adenine dinucleotide (NAD

Indexed as

AdenosineAdenosine TriphosphateADP-ribosyl Cyclase 1Cell LineHumansHypersensitivityLungNADAdenosineAdenosine TriphosphateADP-ribosyl Cyclase 1NADairway smooth muscleasthmaCD38epithelial cells

Identifiers

PMID33120985
PMCPMC7663290
OpenAlexW3094864028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.