Evidence map›Paper›PMID 33120881›Full record

ArticleMolecules (Basel, Switzerland)2020

Copper Ionophores as Novel Antiobesity Therapeutics.

Peter M Meggyesy, Shashank Masaldan, Sharnel A S Clatworthy, Irene Volitakis, Daniel J Eyckens, Kathryn Aston-Mourney, Michael A Cater

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Potential Therapeutic Properties of the Leaf ofPlants (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peter M MeggyesyCentre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia.
Shashank MasaldanCentre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia.ORCID 0000-0003-4960-4983
Sharnel A S ClatworthyCentre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia.
Irene VolitakisMelbourne Dementia Research Centre, The Florey Institute of Neuroscience and Mental Health, Parkville, Victoria 3052, Australia.
Daniel J EyckensInstitute for Frontier Materials, Deakin University, Waurn Ponds, Victoria 3216, Australia.
Kathryn Aston-MourneySchool of Medicine, IMPACT, Institute for Innovation in Physical and Mental Health and Clinical~Translation, Deakin University, Geelong 3220, Australia.ORCID 0000-0003-1412-6715
Michael A CaterCentre for Cellular and Molecular Biology, School of Life and Environmental Sciences, Deakin University, Burwood, Victoria 3125, Australia.

Funding

Deakin University Centre for Molecular and Medical Research Theme Funding
6 · The paper itself

Abstract

The therapeutic utility of the copper ionophore disulfiram was investigated in a diet-induced obesity mouse model (C57BL/6J background), both through administration in feed (0.05 to 1% (

Indexed as

AnimalsAnti-Obesity AgentsBody WeightCopperDisulfiramDose-Response Relationship, DrugIonophoresLiverMiceMice, Inbred C57BLPermeabilityAnti-Obesity AgentsCopperDisulfiramIonophoresAntabusecopperdisulfiramfat metabolismH2(gtsm)ionophoreobesity

Identifiers

PMID33120881
PMCPMC7672559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.