ArticleCancers2020
Reduced SLIT2 is Associated with Increased Cell Proliferation and Arsenic Trioxide Resistance in Acute Promyelocytic Leukemia.
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In one paragraph
Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 18 citations in OpenAlex.
- Efficacy and mechanism of the XPO1 inhibitor selinexor combined with decitabine in T-cell lymphoblastic lymphoma.Annals of hematology · 2025Article
- LncRNA PGM5-AS1 inhibits non-small cell lung cancer progression by targeting miRNA-423-5p/SLIT2 axis.Cancer cell international · 2024Article
- M2 macrophages drive leukemic transformation by imposing resistance to phagocytosis and improving mitochondrial metabolism.Science advances · 2023Article
- The Development and Clinical Applications of Oral Arsenic Trioxide for Acute Promyelocytic Leukaemia and Other Diseases.Pharmaceutics · 2022Review
- DSP107 combines inhibition of CD47/SIRPα axis with activation of 4-1BB to trigger anticancer immunity.Journal of experimental & clinical cancer research : CR · 2022Article
- Bcl-2 hijacks the arsenic trioxide resistance in SH-SY5Y cells.Journal of cellular and molecular medicine · 2022Article
- Acute Promyelocytic Leukemia.Cancers · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
31 authors at 18 institutions in 8 countries.
Isabel WeinhäuserDepartment of Internal Medicine, Department of Medical Images, Hematology, and Clinical Oncology, Medical School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto 14048-900, Brazil.ORCID 0000-0002-6238-2783
Diego A Pereira-MartinsDepartment of Internal Medicine, Department of Medical Images, Hematology, and Clinical Oncology, Medical School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto 14048-900, Brazil.ORCID 0000-0002-3302-4311
Cesar OrtizDepartment of Internal Medicine, Department of Medical Images, Hematology, and Clinical Oncology, Medical School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto 14048-900, Brazil.ORCID 0000-0003-3420-803X
Douglas R SilveiraHematology Division, LIM31, Faculdade de Medicina, University of Sao Paulo, Sao Paulo 05403-000, Brazil.ORCID 0000-0001-5298-9592
Luíse A A SimõesCenter for Cell Based Therapy, University of São Paulo, Ribeirao Preto 14051-060, Brazil.
Thiago M BiancoDepartment of Internal Medicine, Department of Medical Images, Hematology, and Clinical Oncology, Medical School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto 14048-900, Brazil.ORCID 0000-0001-5326-0162
Cleide L AraujoCenter for Cell Based Therapy, University of São Paulo, Ribeirao Preto 14051-060, Brazil.
Luisa C KouryDepartment of Internal Medicine, Department of Medical Images, Hematology, and Clinical Oncology, Medical School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto 14048-900, Brazil.
Raul A M MeloDepartment of Internal Medicine, University of Pernambuco, Recife 50100-130, Brazil.
Rosane I BittencourtHematology Division, Federal University of Rio Grande do Sul, Porto Alegre 96.200-190, Brazil.
Katia PagnanoHematology and Hemotherapy Center, University of Campinas, Campinas 13083-878, Brazil.ORCID 0000-0001-7975-0805
Ricardo PasquiniHematology Division, Federal University of Parana, Curitiba 13083-878, Brazil.
Elenaide C NunesHematology Division, Federal University of Parana, Curitiba 13083-878, Brazil.ORCID 0000-0002-1444-2542
Evandro M FagundesHematology Division, Federal University of Minas Gerais, Belo Horizonte 30130-100, Brazil.
Ana B GloriaHematology Division, Federal University of Minas Gerais, Belo Horizonte 30130-100, Brazil.
Fábio KerbauyHematology Division, Federal University of Sao Paulo, Sao Paulo 04023-062, Brazil.
Maria de Lourdes ChauffailleHematology Division, Federal University of Sao Paulo, Sao Paulo 04023-062, Brazil.
Armand KeatingPrincess Margaret Cancer Centre, Toronto, ON M5G 2C1, Canada.
Martin S TallmanLeukemia Service, Memorial Sloan-Kettering Cancer Center/Weill Cornell Medical College, New York, NY 10065, USA.
Raul C RibeiroDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.ORCID 0000-0002-9956-5647
Richard DillonDepartment of Medical and Molecular Genetics, King's College London School of Medicine, London WC2R 2LS, UK.
Arnold GanserDepartment of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, 30625 Hannover, Germany.
Bob LöwenbergDepartment of Hematology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Peter ValkDepartment of Hematology, Erasmus University Medical Center, 3015 GD Rotterdam, The Netherlands.
Francesco Lo-CocoDepartment of Biopathology, University Tor Vergata, 00133 Rome, Italy.
Miguel A SanzDepartment of Hematology, Hospital Universitari I Politècnic La Fe, 46-009 Valencia, Spain.ORCID 0000-0003-1489-1177
Nancy BerlinerDepartment of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Emanuele AmmatunaDepartment of Experimental Hematology, Cancer Research Centre Groningen, University Medical Centre Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Antonio R Lucena-AraujoDepartment of Genetics, Federal University of Pernambuco, Recife 50670-901, Brazil.ORCID 0000-0003-1694-8958
Jan Jacob SchuringaDepartment of Experimental Hematology, Cancer Research Centre Groningen, University Medical Centre Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Eduardo M RegoCenter for Cell Based Therapy, University of São Paulo, Ribeirao Preto 14051-060, Brazil.
Universidade de São Paulo · BRUniversity Medical Center Groningen · NLErasmus MC · NLUniversidade Federal de Minas Gerais · BRUniversidade Federal de São Paulo · BRUniversidade Federal do Paraná · BRBrigham and Women's Hospital · USInstituto de Salud Carlos III · ESKing's College London · GBMedizinische Hochschule Hannover · DEMemorial Sloan Kettering Cancer Center · USPrincess Margaret Cancer Centre · CASt. Jude Children's Research Hospital · USUniversidade de Pernambuco · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de Pernambuco · BRUniversidade Federal do Rio Grande do Sul · BRUniversity of Rome Tor Vergata · IT
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MFAPESP #2013/08135-2 | #2017/23117-1 | #2015/09228-0NCI NIH HHS P30 CA008748
Abstract
The SLIT-ROBO axis plays an important role in normal stem-cell biology, with possible repercussions on cancer stem cell emergence. Although the Promyelocytic Leukemia (PML) protein can regulate
Indexed as
acute promyelocytic leukemiaATRASLIT2treatment outcomes
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.