ReviewMedicine2020
Central diabetes insipidus unveiled by glucocorticoid therapy in a patient with an empty sella: A case report and literature review.
Review in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Pituitary Metastasis in Lung Cancer Patients: Case Series and Review of the Literature.Current oncology (Toronto, Ont.) · 2026Review
- Glucocorticoid-induced arginine vasopressin deficiency and neurohypophyseal T1-hyperintensity transient switch-off.JCEM case reports · 2026Article
- Central Diabetes Insipidus Following Steroid Replacement for Hypoadrenalism in Pembrolizumab-Induced Hypophysitis.Cureus · 2026Article
- Central Diabetes Insipidus in Suprasellar Germ Cell Tumor Paradoxically Presenting With Oliguria.Clinical case reports · 2026Article
- An Update on Advances in Hypopituitarism: Etiology, Diagnosis, and Current Management.Journal of clinical medicine · 2024Review
- Pituitary metastasis as the first manifestation of lung carcinoma.Clinical case reports · 2022Article
- Central hypothyroidism with myxoedema: a less known but clinically challenging presentation.BMJ case reports · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleSome diseases contribute to hypopituitarism without clinical manifestations and the glucocorticoid therapy may unveil central diabetes insipidus. The condition is rare and usually causes problems for clinical physicians. PATIENT CONCERNS: A 59-year-old woman presented to our hospital due to facial numbness and persistent eyelid heaviness. DIAGNOSIS: Physical examination and cerebrospinal fluid examination supported a diagnosis of Guillain-Barre[Combining Acute Accent] syndrome. Magnetic resonance imaging showed an empty sella. Hormone test indicated hypopituitarism.
interventionsThe patient received intravenous immunoglobulin and glucocorticoid. Central diabetes insipidus appeared after 20 days. Subsequently, the patient was prescribed 1-desamino-8-D-arginine vasopressin and prednisone. OUTCOMES: During 6 months' follow-up, the patient's urine output was gradually reduced to normal level. LESSONS: This case indicated that hypopituitarism may be caused by an empty sella and be masked by adrenal insufficiency. Central diabetes insipidus may present after glucocorticoid therapy.
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