Evidence map›Paper›PMID 33120784›Full record

ArticleMedicine2020

Quality of life among patients with autoimmune hepatitis in remission: A comparative study.

Atsushi Takahashi, Masanori Abe, Tetsuya Yasunaka, Teruko Arinaga-Hino, Kazumichi Abe, Akinobu Takaki, Takuji Torimura, Mikio Zeniya, Kaname Yoshizawea, Jong-Hon Kang and 6 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 1 country.

Atsushi TakahashiDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Hikarigaoka, Fukushima.
Masanori AbeDepartment of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Shitsukawa, To-on, Ehime.
Tetsuya YasunakaDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama-city.
Teruko Arinaga-HinoDepartment of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume-shi, Fukuoka.
Kazumichi AbeDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Hikarigaoka, Fukushima.
Akinobu TakakiDepartment of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama-city.
Takuji TorimuraDepartment of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume-shi, Fukuoka.
Mikio ZeniyaSanno Medical Center, International University of Health and Welfare, 8-10-16 Akasaka, Minato-ku, Tokyo.
Kaname YoshizaweaDepartment of Gastroenterology, National Hospital Organization, Shinshu Ueda Medical Center, 1-27-21 Midorigaoka, Ueda-City, Nagano.
Jong-Hon KangCenter for Gastroenterology, Teine Keijinkai Hospital, 1-12 Maeda, Teine-ku, Sapprro.
Yoshiyuki SuzukiDepartment of Hepatology, Toranomon Hospital, Toranomon 2-2-2, Minato-ku.
Nobuhiro NakamotoDepartment of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo.
Ayano InuiDepartment of Pediatric Hepatology and Gastroenterology, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama-City, Kanagawa.
Atsushi TanakaDepartment of Medicine, Teikyo University School of Medicine, 2-11-1, Kaga, Itabashi-ku.
Hajime TakikawaFaculty of Medical Technology, Teikyo University, 2-11-1, Kaga, Itabashi-ku, Tokyo, Japan.
Hiromasa OhiraDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Hikarigaoka, Fukushima.
Fukushima Medical University · JPKurume University · JPOkayama University · JPEhime University · JPInternational University of Health and Welfare · JPKeio University · JPNational Hospital Organization · JPTeikyo University · JPTeine Keijinkai Hospital · JPToranomon Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Health-related quality of life (HRQOL) is lower in individuals with autoimmune hepatitis (AIH) than in the general population. However, previous evaluations of HRQOL for AIH have included a broad range of disease activities. The aim of this study was to clarify HRQOL among patients with AIH in remission.We assessed HRQOL in patients with AIH in remission, patients with chronic hepatitis C (CHC) with eradicated hepatitis C virus (HCV) and patients with primary biliary cholangitis (PBC) using the Japanese version of the Chronic Liver Disease Questionnaire (CLDQ).Participants comprised 62 patients with AIH in remission, 39 patients with CHC with eradicated HCV and 66 patients with PBC. Median ages of patients were 63, 69, and 64 years, respectively. Overall score (5.6 vs 5.9, P = .02) and fatigue (5.2 vs 5.6, P = .01) and worry (5.6 vs 6.0, P = .01) domain scores of the CLDQ were significantly lower in patients with AIH in remission than in CHC with eradicated HCV, and similar to scores except for the systemic symptoms domain in patients with PBC. Disease duration was associated with lower scores on systemic symptoms and activity domains of the CLDQ in patients with AIH in remission.Patients with AIH in remission show impaired HRQOL associated with disease duration.

Indexed as

Hepatitis, AutoimmuneQuality of LifeAgedFemaleHepatitis C, ChronicHumansLiver Cirrhosis, BiliaryMaleMiddle AgedRemission InductionSelf Report

Identifiers

PMID33120784
PMCPMC7581115
OpenAlexW3094607216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.