ArticleIndian journal of ophthalmology2020
Malignant tumors of the eyelid in India: A multicenter, multizone study on clinicopathologic features and outcomes.
Article in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 25 citations in OpenAlex.
- Risk factors for local recurrence and metastasis of eyelid sebaceous carcinoma after complete excision: A large cohort study in Japan.Indian journal of ophthalmology · 2026Article
- Malignant Eyelid Tumors in Italy (2020-2024): Toward Personalized Epidemiologic Insights from Two Referral Centers.Journal of personalized medicine · 2025Article
- Clinical presentation and prognostic factors of eyelid sebaceous carcinoma.Japanese journal of ophthalmology · 2025Article
- A Systematic Review and Meta-Analysis of Ocular and Periocular Basal Cell Carcinoma with First-Time Description of Dermoscopic and Reflectance Confocal Microscopy Features of Caruncle Basal Cell Carcinoma.Diagnostics (Basel, Switzerland) · 2025Review
- Epidemiological profile and clinical characteristics of ocular and periocular tumors in North and Central India.Indian journal of ophthalmology · 2025Observational
- Clinical and Dermoscopic Patterns of Basal Cell Carcinoma and Its Mimickers in Skin of Color: A Practical Summary.Medicina (Kaunas, Lithuania) · 2024Review
- Neoadjuvant chemotherapy for advanced eyelid and periocular sebaceous gland carcinoma: a study of 25 cases.International ophthalmology · 2024Article
- Eyelid sebaceous gland carcinoma: a protocol for a systematic review and meta-analysis of clinicopathological studies of prevalence.BMJ open · 2024Article
- HPV-Associated Squamous Cell Carcinoma of the Eyelid: Diagnostic Utility of p16 Immunohistochemistry and mRNA In Situ Hybridization.Head and neck pathology · 2023Article
- Prevalence of and Associated Factors for Eyelid Cancer in the American Academy of Ophthalmology Intelligent Research in Sight Registry.Ophthalmology science · 2023Article
- Clinicopathological features of patients with wide local excision of eyelid malignant neoplasms: a more than five years retrospective study from China.BMC ophthalmology · 2022Article
- The epidemiology of adults' eyelid malignancies in Germany between 2009 and 2015; An analysis of 42,710 patients' data.European journal of ophthalmology · 2022Article
- Chondrocutaneous conchal graft for optimal reconstruction of full-thickness lower eyelid defect: a reconstructive challenge.BMJ case reports · 2022Article
- Commentary: Cryotherapy and the sebaceous glands.Indian journal of ophthalmology · 2022Article
- The spectrum and clinicopathological correlation of eyelid lesions: Twenty years' experience at a tertiary eye care center in South India.Indian journal of ophthalmology · 2022Article
- Comment on: Malignant tumors of the eyelid in India: A multicenter, multizone study on clinicopathologic features and outcomes.Indian journal of ophthalmology · 2021Article
- Malignant tumors of the eyelid - To err is human, to learn divine.Indian journal of ophthalmology · 2020Article
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5 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyze data on eyelid malignancy in India, clinical and pathologic features, and outcomes.
methodsA multicentre study, from oculoplastic practices in four geographic zones in India. The centers perform similar documentation and protocol-based management for eyelid tumors. Clinical features, pathology, American Joint Committee on Cancer (AJCC) class, management, and the outcomes were analyzed.
resultsThe study included 129 patients, with slight female preponderance and mean age 62.7 years. The median delay to the consultation was 9 months. Rural patients traveled a mean distance of 115.2 km; there was no difference between the city and outstation patients in the delay to consultation or follow up. Pathology included 55/129 (42.6%) sebaceous gland carcinoma (SGC), 47/129 (36.4%) basal cell carcinoma (BCC), squamous cell carcinoma (SCC) in 15 (11.6%), and 12 (9.3%) other tumors. Commonest AJCC class was T2b/T3a in 80/111 (72%), invasion of the orbit was present in 16 (12.4%). Surgery with margin clearance was performed in 103. With a mean follow-up of 21.44 months, local recurrence and/or metastasis were seen in 12%. The diagnosis of SGC was strongly associated with adverse outcomes (odds ratio: 7.36). On multiple logistic regression analysis, diagnosis of SGC (P = 0.011) was significant in having adverse outcomes.
conclusionThe multicenter Indian data shows the highest prevalence of SGC, with the commonest AJCC class T2b. Most tumors were locally resectable at presentation. The histopathologic diagnosis of SGC is the factor strongly associated with adverse outcomes.
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