ArticleIndian journal of ophthalmology2020
Evaluation of corneal topography and tomography in fellow eyes of unilateral keratoconus patients for early detection of subclinical keratoconus.
Article in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Early Detection of Keratoconus: Diagnostic Advances and Their Impact on Visual Outcomes: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Improving the diagnostic efficiency of forme fruste keratoconus by a new combined model with Fourier parameters and corneal epithelial aberrations.Eye (London, England) · 2025Article
- Extremely asymmetric ectasia: Tomographically unilateral keratoconus.Acta ophthalmologica · 2025Article
- Strategies for Early Keratoconus Diagnosis: A Narrative Review of Evaluating Affordable and Effective Detection Techniques.Journal of clinical medicine · 2025Review
- Multi-modal imaging for the detection of early keratoconus: a narrative review.Eye and vision (London, England) · 2024Review
- Keratoconus: imaging modalities and management.Medical hypothesis, discovery & innovation ophthalmology journal · 2024Review
- Revisiting Pentacam Parameters in the Diagnosis of Subclinical and Mild Keratoconus Based on Different Grading System DefinitionsTurkish journal of ophthalmology · 2023Article
- Prevalence of subclinical keratoconus and impact on adults undergoing routine, uncomplicated age-related cataract extraction.Frontiers in ophthalmology · 2023Article
- Could Corneal Densitometry be a Progression Criterion for Subclinical Keratoconus?Beyoglu eye journal · 2023Article
- Keratoconus Classification with Convolutional Neural Networks Using Segmentation and Index Quantification of Eye Topography Images by Particle Swarm Optimisation.BioMed research international · 2022Article
- Evaluation of Personality Features and Mental State of Keratoconus Patients.Beyoglu eye journal · 2021Article
- Toric intraocular lens: A literature review.Taiwan journal of ophthalmologyReview
- Comprehensive evaluation of oculus pentacam in subclinical keratoconus and clinical keratoconus patients at different stages.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
- Role of corneal epithelial mapping, Corvis biomechanical index, and artificial intelligence-based tomographic biomechanical index in diagnosing spectrum of keratoconus.Oman journal of ophthalmologyArticle
- Comparison of Corneal Tomography Parameters in the Diagnosis of Keratoconus in Early and Late Pediatric Age Group.Middle East African journal of ophthalmologyArticle
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo analyse topographic and tomographic changes in fellow eyes of unilateral keratoconus patients by comparing them with normal eyes.
methodsThis five-year retrospective observational comparative case study included 15 advanced keratoconus eyes of unilateral keratoconus (KCN group), 15 normal fellow eyes of unilateral keratoconus (Fellow eye group) and 34 eyes of normal refractive surgery candidates (Normal group). Topographic and tomographic data, data from enhanced elevation maps, and keratoconus indices were measured in all study eyes using Pentacam. Receiver operating characteristic (ROC) curves were used to evaluate the area under the curve (AUC), sensitivity and specificity of each parameter and identify cut-off points in discriminating between the fellow and normal eyes.
resultsCorneal thickness at the apex (CTA, P = 0.001) and at the thinnest point (CTT, P < 0.001), corneal volume (CV, P = 0.007), Belin/Ambrosio Enhanced Ectasia Display (BAD) - thinnest point (Dt, P = 0.002) and thinnest point displacement (Da, P = 0.002) were significantly lower in the fellow group compared to eyes of normal subjects. On ROC curve analysis, the most efficient distinguishing indices between the fellow group and normal controls were BAD - overall D value (AUC = 0.859), Dt (AUC =0.827), Da (AUC = 0.789) followed by pachymetric progression index maximum (AUC = 0.741).
conclusionBAD-D value and pachymetric progression index could be useful in detecting the earliest form of subclinical keratoconus. However, every single parameter alone is not enough to detect early changes; a combination of different data is required to distinguish subclinical keratoconus.
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