ArticleJournal of applied clinical medical physics2020
Effect of setup error in the single-isocenter technique on stereotactic radiosurgery for multiple brain metastases.
Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Geometric and dosimetric effects of an automated clustering and plan optimization pipeline for multiple brain metastasis radiosurgery.Journal of applied clinical medical physics · 2026Article
- Assessing the role of plan complexity and target geometry through multi-institutional gel based end-to-end QA in multi-focal single isocenter stereotactic radiosurgery.Journal of applied clinical medical physics · 2026Article
- Hybrid geometric and evolutionary optimization framework for radiosurgery planning: isocenter selection and angle optimization for multiple brain metastases.Radiological physics and technology · 2026Article
- Application of support vector machines for modeling dosimetric uncertainty in radiotherapy planning.Radiological physics and technology · 2026Article
- Distance-adaptive geometric margins for residual rotational uncertainty in single-isocenter multitarget stereotactic radiosurgery.Physics and imaging in radiation oncology · 2026Article
- Dosimetric intercomparison for stereotactic radiotherapy of multiple brain metastases.Physics and imaging in radiation oncology · 2026Article
- A multi-institutional survey on radiosurgery for multiple brain metastases in Latin America.Physical and engineering sciences in medicine · 2026Article
- The feasibility of using coplanar-only VMAT combined with "Treat" function to replace non-coplanar VMAT for SRS of 2 to 6 brain metastases.Quantitative imaging in medicine and surgery · 2025Article
- Quality and Dosimetric Accuracy of Linac-Based Single-Isocenter Treatment Plans for Four to Eighteen Brain Metastases.Cancers · 2025Article
- Clinical technique: evaluation of detection accuracy in surface-guided radiation therapy using CT references from different treatment planning systems.Radiological physics and technology · 2025Article
- Optimizing anisotropic margins in single-isocenter multiple brain metastases radiosurgery using regressor strategies: A multi-institutional validation study.Journal of applied clinical medical physics · 2025Article
- Comparison of single- and multi-isocenter planning with Dynamic WaveArc for multiple brain metastases.Journal of radiation research · 2025Article
- Assessing tumor volumetric reduction with consideration for setup errors based on mathematical tumor model and microdosimetric kinetic model in single-isocenter VMAT for brain metastases.Physical and engineering sciences in medicine · 2024Article
- Impact of setup errors on the robustness of linac-based single-isocenter coplanar and non-coplanar VMAT plans for multiple brain metastases.Journal of applied clinical medical physics · 2024Article
- Stereotactic Radiosurgery in the Management of Brain Metastases: A Case-Based Radiosurgery Society Practice Guideline.Advances in radiation oncology · 2024Review
- Multicomponent mathematical model for tumor volume calculation with setup error using single-isocenter stereotactic radiotherapy for multiple brain metastases.Physical and engineering sciences in medicine · 2023Article
- Automatic measurement of beam-positioning accuracy at off-isocenter positions.Journal of applied clinical medical physics · 2023Article
- Evaluation of the ability of the Brainlab Elements Cranial Distortion Correction algorithm to correct clinically relevant MRI distortions for cranial SRT.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022Article
- Impact of systematic MLC positional uncertainties on the quality of single-isocenter multi-target VMAT-SRS treatment plans.Journal of applied clinical medical physics · 2022Article
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Authors and funding
13 authors.
Funding
Abstract
In conventional stereotactic radiosurgery (SRS), treatment of multiple brain metastases using multiple isocenters is time-consuming resulting in long dose delivery times for patients. A single-isocenter technique has been developed which enables the simultaneous irradiation of multiple targets at one isocenter. This technique requires accurate positioning of the patient to ensure optimal dose coverage. We evaluated the effect of six degrees of freedom (6DoF) setup errors in patient setups on SRS dose distributions for multiple brain metastases using a single-isocenter technique. We used simulated spherical gross tumor volumes (GTVs) with diameters ranging from 1.0 to 3.0 cm. The distance from the isocenter to the target's center was varied from 0 to 15 cm. We created dose distributions so that each target was entirely covered by 100% of the prescribed dose. The target's position vectors were rotated from 0°-2.0° and translated from 0-1.0 mm with respect to the three axes in space. The reduction in dose coverage for the targets for each setup error was calculated and compared with zero setup error. The calculated margins for the GTV necessary to satisfy the tolerance values for loss of GTV coverage of 3% to 10% were defined as coverage-based margins. In addition, the maximum isocenter to target distance for different 6DoF setup errors was calculated to satisfy the tolerance values. The dose coverage reduction and coverage-based margins increased as the target diameter decreased, and the distance and 6DoF setup error increased. An increase in setup error when a single-isocenter technique is used may increase the risk of missing the tumor; this risk increases with increasing distance from the isocenter and decreasing tumor size.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.