Evidence map›Paper›PMID 33119828›Full record

ArticleDoklady. Biochemistry and biophysics2020

Expression of Protein Kinases RIPK-1 and RIPK-3 in Mouse and Human Hair Follicle.

E I Morgun, E D Pozdniakova, E A Vorotelyak

Abstract read
PubMed Publisher
In one paragraph

Article in Doklady. Biochemistry and biophysics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. The Involvement of RIPK1 in Alopecia Areata.International journal of molecular sciences · 2025
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

E I MorgunMoscow Institute of Physics and Technology (State University), Dolgoprudny, Moscow, Russia. lady.morgun2016@yandex.ru.
E D PozdniakovaMoscow State University, Moscow, Russia.
E A VorotelyakKoltzov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia.
Koltzov Institute of Developmental Biology · RULomonosov Moscow State University · RUMoscow Institute of Physics and Technology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Expression of cell death regulators RIPK-1 and RIPK-3 in mouse and human hair follicle structures was studied by immunohistochemistry. At anagen and catagen stages of mouse hair follicle, RIPK-1+ cells were located in the inner root sheath, whereas RIPK-3+ cells were found in the inner and outer root sheath, dermal papilla, and interfollicular epidermis. RIPK-1 expression intensity was low in the early anagen and increased as mature anagen and catagen approached. RIPK-1+ and RIPK-3+ cells were also found in human hair follicle. It is assumed that the role of necroptosis markers in hair follicle life activity is independent of programmed cell death and that they may have yet unknown functions and take part in noncanonical signal cascades.

Indexed as

AnimalsApoptosisHair FollicleHumansImmunohistochemistryMaleMiceMice, Inbred C57BLReceptor-Interacting Protein Serine-Threonine KinasesSkinReceptor-Interacting Protein Serine-Threonine KinasesRIPK1 protein, humanRipk1 protein, mouseRIPK3 protein, humanRipk3 protein, mouseanagencatagenhair folliclenecroptosisprogrammed cell deathRIPK-1RIPK-3

Identifiers

PMID33119828
OpenAlexW3097414369

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.