Evidence map›Paper›PMID 33119726›Full record

ReviewPLoS pathogens2020

The prion-like phenomenon in Alzheimer's disease: Evidence of pathology transmission in humans.

Ruben Gomez-Gutierrez, Rodrigo Morales

Open access · goldAbstract readReview
In one paragraph

Review in PLoS pathogens, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 43 citations in OpenAlex.

  1. How does type 2 diabetes modify the risk of Alzheimer's disease?Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  2. Review
  3. Review
  4. Peripheral proteinopathy in neurodegenerative diseases.Translational neurodegeneration · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Colonoscopy and Subsequent Risk of Parkinson's Disease.Journal of Parkinson's disease · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. The Prion Basis of Progressive Neurodegenerative Disorders.Interdisciplinary perspectives on infectious diseases · 2023
    Review
  16. Article
  17. Review
  18. Transgenic Mouse Models of Alzheimer's Disease: An Integrative Analysis.International journal of molecular sciences · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Ruben Gomez-GutierrezDepartment of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.ORCID 0000-0001-9134-4375
Rodrigo MoralesDepartment of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.ORCID 0000-0001-7766-5770
Baylor College of Medicine · USUniversidad Bernardo O'Higgins · CL

Funding

Role of circulating Abeta seeds and peripheral tissue damage in Alzheimer's disease pathogenesisRF1AG059321 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MORALES, RODRIGO, SOTO, CLAUDIO · 2020 to 2020
$2.9M
Isolation, characterization and pathogenic role of self-propagating conformational amyloid-beta strainsR56AG061878 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MORALES, RODRIGO, SOTO, CLAUDIO · 2018 to 2018
$551k
NIA NIH HHS R56 AG061878NIA NIH HHS RF1 AG059321
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesHumansPrionsProtein FoldingProteostasis DeficienciesTauopathiesAmyloid beta-PeptidesPrions

Identifiers

PMID33119726
PMCPMC7595341
OpenAlexW3097669757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.