Evidence map›Paper›PMID 33119649›Full record

ArticlePloS one2020

Long term outcomes for elderly patients after emergency intensive care admission: A cohort study.

Ged Dempsey, Dan Hungerford, Phil McHale, Lauren McGarey, Edward Benison, Ben Morton

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ged DempseyLiverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.ORCID 0000-0003-2014-1022
Dan HungerfordInstitute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom.
Phil McHaleDepartment of Public Health and Policy, Institute of Population Health Sciences, University of Liverpool, Liverpool, United Kingdom.
Lauren McGareyLiverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.
Edward BenisonLiverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.ORCID 0000-0001-6986-7153
Ben MortonLiverpool University Hospitals NHS Foundation Trust, Liverpool, United Kingdom.ORCID 0000-0002-6164-2854

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElderly patients (≥ 80 years of age) surviving an episode of critical illness suffer long-term morbidity and risk of mortality. Identifying high risk groups could assist in informing discussions with patients and families.

aimTo determine factors associated with long-term survival following ICU admission.

designA cohort study of patients aged ≥ 80 years of age admitted to the ICU as an emergency.

methodsPatients admitted from January 2010 to December 2018 were included in the study. Primary outcome was five year survival. Mortality was assessed using a multivariable flexible parametric survival analysis adjusted for demographics, and clinically relevant covariates.

resultsThere were 828 patients. Mean age was 84 years (SD 3.2) and 419 (51%) were male. Patients were categorised into medical (423 (51%)) and surgical (405 (49%)) admissions. Adjusted hazard ratios (aHR) for mortality were highest for serum lactate (>8 mmol/l aHR 2.56 (C.I. 1.79-3.67)), lowest systolic blood pressure (< 70 mmHg aHR 2.04 (C.I. 1.36-3.05)) and pH (< 7.05 aHR 4.70 (C.I 2.67-8.21)). There were no survivors beyond one year with severe abnormalities of pH and lactate (< 7.05 and > 8 mmol/l respectively). Relative survival for medical patients was below that expected for the general population for the duration of the study.

conclusionOverall five-year survival was 27%. For medical and surgical patients it was 19% and 35% respectively. Survival at 30 days and one year was 61% and 46%. The presence of features of circulatory shock predicted poor short and long term survival.

Indexed as

Critical CareEmergency Medical ServicesIntensive Care UnitsPatient AdmissionAged, 80 and overDisease-Free SurvivalFemaleHumansMaleSurvival Rate

Identifiers

PMID33119649
PMCPMC7595304

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.